Dr. Sharon Hausman-Cohen: How to Address Dementia, Autism, and Other Chronic Diseases with Genomic Testing

Mark Hyman

Feb 21, 2024

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Dr. Sharon Hausman-Cohen is the Chief Medical Officer and co-founder of IntellxxDNA and has been in the field of integrative medicine for over 25 years. She is the co-author of many publications and a textbook chapter on using genomics to improve outcomes in cognitive decline and autism.

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In this episode we discuss (audio version / Apple Subscriber version):

What are genes and what do they do? (6:37 / 4:33)
Genetic predisposition does not mean predestined (9:22 / 7:18)
The difference between genetics vs genomics (13:10 / 11:06)
Polygenic risk scoring for chronic disease (18:18 / 16:14)
Dementia risk and treatment (33:59 / 29:24)
Mental and cognitive health issues in children (46:00 / 41:25)
The similarities between Autism and Alzheimer’s patients (49:49 / 45:14)
My genomic test results, specifically related to detoxification and osteoporosis (52:21 / 47:45)
Genetic vs genomic testing (1:06:29 / 1:01:54)

Learn more at IntellxxDNA.com.

Mindsip insights from this episode:

Recognize hidden genetic osteoporosis risk from ALDH7A1 gene

You can have a high genetic risk for osteoporosis from the ALDH7A1 gene, which impairs bone-building in youth, even if you have a very active lifestyle.

#genetics

#osteoporosis

Manage air pollution sensitivity with resveratrol

A specific overactive gene, CYP1B1, can make an individual highly sensitive to the toxic and carcinogenic effects of air pollution, a risk that can be managed with resveratrol.

#air-quality

#genetics

Investigate vitamin C recycling to support ADHD focus

Some children diagnosed with ADHD may actually have a genetic inability to recycle vitamin C, which is essential for producing the brain chemical norepinephrine needed for focus.

#ADHD

#vitamin-C

Address hypercoagulability to combat dementia risk

For some people, dementia is not caused by amyloid plaques but by hypercoagulability (thick blood), which can be addressed with supplements like Pycnogenol and Nattokinase.

#dementia

#supplement

Maximize metabolism with intense exercise for FTO gene variant

For individuals with the FTO gene variant, intense exercise is more effective at improving metabolism than any supplement.

#exercise

#genetics

Address gaps in Alzheimer's risk scores for comprehensive assessment

Standard polygenic risk scores for Alzheimer's are often incomplete because they fail to account for critical factors like detoxification pathways, inflammation, and brain blood flow.

#Alzheimer's

#risk

Investigate genetic links between autism and Alzheimer's disease

The genetic predisposition profiles for children with autism and adults with Alzheimer's disease are often strikingly similar, involving issues with methylation and inflammation.

#Alzheimer's

#autism

Discover C15 fatty acid for superior cellular benefits

The essential fatty acid C15, found in the supplement Fatty15, was shown in research to have more cellular benefits than top longevity drugs like rapamycin and metformin.

#C15

#supplement

Mark Hyman

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