
How much does Reversing Plaque lower your Heart Attack risk?
Physionic
Apr 25, 2025
Mindsip insights from this episode:
Achieve 1% plaque reduction to lower cardiovascular event risk by 19%
After adjusting for factors like age, LDL, and blood pressure, a 1% reversal in arterial plaque volume is associated with a 19% reduction in cardiovascular event risk.
Recognize true risk reduction from reversing plaque exceeds 19%
The true risk reduction from reversing plaque may be even greater than 19% because many studies compared treatments against low-dose statins, not a true placebo.
Address inflammation to stabilize plaque and reduce rupture risk
A major component of dangerous plaque is the inflammatory 'necrotic core' formed by dead immune cells, which destabilizes the plaque and makes it more likely to rupture.
Monitor fibrotic cap thickness to assess plaque risk
The thickness of the fibrotic cap that cells place on top of plaque is a key risk factor, as a thinner cap is more prone to breaking than a thicker one.
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