The Drugs Dr Brad Takes for a Longer, Healthier Life
Brad Stanfield
Jun 10, 2025
Mindsip insights from this episode:
Utilize Empagliflozin to potentially extend lifespan by 10%
The SGLT2 inhibitor Empagliflozin (Jardiance) may extend male lifespan by 10% based on mouse studies from the Intervention Testing Program.
Maintain blood pressure below 120 for optimal health
A blood pressure reading of 140 is not considered okay, especially for a young person, and the target should be below 120.
Acknowledge genetics in managing blood pressure and cholesterol
Even with a perfect diet and exercise routine, your genetic makeup may require you to take medication for high blood pressure or cholesterol.
Utilize multiple low-dose medications for blood pressure and cholesterol management
For blood pressure and cholesterol, it's better to use lower doses of multiple medications attacking different pathways than to increase the dose of one pill.
Cut Empagliflozin tablets to save on medication costs
To save money on the medication Empagliflozin (Jardiance), you can get the 25mg tablet and cut it in half for a 12.5mg dose.
Aim for LDL cholesterol levels of 50-60 mg/dL to prevent plaque development
The PESA study suggests that an LDL cholesterol level of 50-60 mg/dL is optimal to prevent any plaque development in blood vessels.
Combine Ezetimibe with statins to effectively lower LDL
Adding Ezetimibe, which blocks cholesterol absorption in the gut, to a statin, which reduces cholesterol production in the liver, can effectively lower LDL.
Choose pravastatin to minimize diabetes risk
Pravastatin is a lower-potency statin with the lowest risk of causing new-onset diabetes, whereas the high-potency Rosuvastatin has the highest risk.
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