The Longevity Code: How Purpose, Connection, and Science Are Rewriting Aging Episode Description:
Mark Hyman
Jul 21, 2025
Mindsip insights from this episode:
Utilize AI heart scans to identify dangerous soft plaque
AI-powered heart scans can now distinguish between safe, calcified plaque and dangerous soft plaque, which is the type that can rupture and cause a heart attack.
Reevaluate longevity in light of evolutionary design
We likely weren't designed to live past age 30, which is why diseases of aging like cancer and heart disease were never evolutionarily selected against.
Understand immune scars left by viruses to protect health
Viruses like SARS-CoV-2 can leave 'immune scars,' which are epigenetic marks that permanently alter your immune system's function.
Combat loneliness to reduce health risks equivalent to heavy smoking
Being lonely and socially isolated is equivalent to the health risk of smoking two packs of cigarettes a day.
Engage in loving conversations to activate healing genes
Loving conversations can literally turn on your anti-inflammatory and healing genes, while conflictual ones increase stress hormones and inflammation.
Prioritize relationships for a long, happy, and healthy life
An 80-year Harvard study concluded that good relationships, not career achievement, diet, or exercise, were the most important determinant of a long, happy, and healthy life.
Access cutting-edge longevity drugs through research programs
A program called 'Edge' gives a small number of members access to participate in research protocols for investigational drugs like rapamycin and therapies like total plasma exchange.
Embrace preventative imaging to catch disease early
A new health insurance model is emerging that provides extensive preventative imaging for free to catch disease early, rather than just paying for treatment after you get sick.
Get annual digital body upload for early health issue detection
Every year, you can get a 'digital upload' including a full-body MRI and AI-powered coronary scan to find issues like cancer or aneurysms before they become a problem.
More from
Mark Hyman
Rethinking ADHD: Root Causes, Real Healing, and the Power of Functional Medicine
How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol
Psychedelics, Depression, and the Brain: A Breakthrough Framework for Mental Health
What If We Got Sunlight All Wrong? The Truth About Vitamin D & Chronic Disease
Bonus Episode: Treating High Blood Pressure at the UltraWellness Center
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