Your Penis Is a Longevity Organ (Here's How to Hack It)

Dave Asprey

Mar 12, 2026

Episode description

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it.

-Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR

Host Dave Asprey sits down with Dr. Justin Houman, a nationally recognized urologist and Assistant Professor of Urology at Cedars-Sinai Medical Center. Fellowship-trained and specializing in men's health, male fertility, and sexual medicine, Dr. Houman combines cutting-edge medical advancements with holistic lifestyle strategies to help men optimize testosterone, sexual health, and reproductive performance at every age.

Together, Dave and Dr. Houman tear through the myths, the bad science, and the outdated medical dogma around testosterone, erectile function, fertility, and male sexual health. They cover everything from why testosterone levels have collapsed in a single generation, to the real story behind the FDA black box warning, to practical protocols for men who want to optimize without sacrificing fertility. This is the masterclass on men's health that no one else is having on record.

This is essential listening for anyone serious about biohacking, longevity, human performance, hormone optimization, brain optimization, anti-aging, functional medicine, mitochondria, and Smarter Not Harder approaches to male health.

You'll Learn:

Why testosterone levels in 40-year-old men are 30 percent lower than their fathers and what is driving the collapse
How low testosterone connects to anxiety, depression, high cholesterol, blood sugar dysregulation, and all-cause mortality risk
The truth about the original testosterone and heart attack study and why it still has not been retracted
How to preserve fertility while on TRT using Clomid, enclomiphene, and HCG
Why daily low-dose Cialis is one of the cheapest and most effective longevity drugs available
What shockwave therapy, PRP, exosomes, and Botox injections actually do for erectile function
How red light therapy at 660 and 850 nanometers supports testosterone production and nocturnal erections
The supplement stack including ashwagandha, tongkat ali, fadogia agrestis, and creatine that supports healthy hormone levels
Why porn-induced ED is epidemic in young men and how to reverse it
How PT-141 and peptides fit into a complete male optimization protocol

Thank you to our sponsors!

Pre-order Arthur Brook's new book today at themeaningofyourlife.com. You can also see Arthur speak live at the 2026 Beyond Biohacking Conference
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Mindsip insights from this episode:

Avoid chronic cardio to maintain testosterone levels

Overtraining, especially chronic long-distance cardio like marathon running, puts the body under constant stress and consistently leads to lower testosterone levels.

#cardio

#testosterone

Utilize Botox injections to enhance erections and reduce ED medication dosage

Injecting Botox into the penis helps relax smooth muscle to increase blood flow, which can enhance erections and allow users to lower their dose of ED medications like Cialis.

#blood-flow

#erection

Recognize and address Post-Orgasmic Illness Syndrome in men

Some men experience a real condition called Post-Orgasmic Illness Syndrome (POIS), where they are highly sensitive to the post-ejaculation prolactin spike, leading to negative symptoms.

#orgasm

prolactin

Preserve fertility during TRT with Clomiphene or HCG

While TRT shuts down sperm production, fertility can be preserved or restored by using medications like Clomiphene or HCG to stimulate natural testicular function.

#fertility

#TRT

Disprove flawed testosterone study linking heart attack risk

The original 1990s study linking testosterone to increased heart attack risk was flawed and has since been disproven by over 24 studies, yet it has never been redacted.

#heart

#testosterone

Shorten refractory period with Cabergoline dose

You can blunt the post-ejaculation prolactin spike and shorten the refractory period by taking a small dose of the pharmaceutical Cabergoline.

#biohacking

Address declining testosterone levels through lifestyle changes

A 40-year-old man today has approximately 30% lower testosterone levels than his father had at the same age due to modern lifestyle factors.

#testosterone

Utilize shockwave therapy for penile enhancement and longevity

Shockwave therapy is considered the best regenerative option for erection longevity as it creates new blood vessel growth and can reverse some age-related penile shrinkage.

#regeneration

#shockwave-therapy

Take daily Cialis for systemic benefits and longevity

A daily low dose of Cialis (5mg) is recommended for men starting in their late 30s due to its systemic benefits, including a reduction in dementia and cardiac risk.

#longevity

Address anxiety to combat erectile dysfunction in young men

For men under the age of 35, erectile dysfunction is caused by anxiety 98% of the time, often fueled by unrealistic expectations from pornography and social media.