The Science of Living Longer: Diet, Supplements, & Sleep | Bryan Johnson
Mark Hyman
10 jul 2024
Mindsip insights from this episode:
Achieve elite muscle mass with a vegan, calorie-restricted diet
Contrary to popular belief, he has demonstrated that a vegan, calorie-restricted diet can achieve top-percentile muscle mass, bone density, and cardiovascular fitness.
Utilize longevity drug stack for enhanced lifespan
He takes a combination of promising longevity drugs, including Metformin, Acarbose, Rapamycin, and the senolytic drug Dasatinib.
Fire your evening self to regain control over food choices
To break bad habits, he created a persona for his self-destructive evening self and 'fired' him from making food decisions, a psychological trick that gave him control.
Simplify your workout with basic exercises for all muscles
Despite his physique, his daily one-hour workout is basic, focusing on stretching every muscle, low-weight/reasonable-rep exercises, and cardio, without needing fancy equipment.
Address death as a critical problem to solve
His entire project began by looking for a problem to solve in the 'negative space' outside of mainstream ideas, leading him to be one of the first to seriously tackle death.
Correct posture to reverse brain aging by 13 years
He discovered that poor posture was contributing to intracranial pressure and white matter lesions in his brain, which he was able to reverse by the equivalent of 13 years through posture correction.
Prioritize sleep discipline for perfect rest
He achieved a perfect WHOOP sleep score for eight months straight by prioritizing sleep above all else, which included finishing all his meals by 11 AM.
Optimize every calorie for measurable benefits
His diet is ruthlessly optimized so that every single calorie consumed must have a specific, measurable, and beneficial function in the body.
More from
Mark Hyman
How OpenAI Is Helping People Take Control of Their Health | Fidji Simo
Office Hours: Cholesterol and Heart Disease — What I’ve Changed My Mind About
Why Men’s Fertility Is Collapsing and What It Means for Our Future | Dr. Michael L. Eisenberg
Office Hours: Preparing Your Body for Pregnancy — Fertility, Nutrition & Hormones
Fix the Brain, Change the Mind: Root-Cause Psychiatry with Dr. Robert Hedaya
You also might be interested in
Aging Starts In Your Legs (Here’s The Fix)
The Surprising Science Of Injecting Young Blood, Salmon Sperm & Stem Cells Into Your Face (And Other Places) With Dr. Khanh Nguyen
How To Be "Forever Strong", Creating The Right Amount of FRICTION In Your Life, Official Protein Rules & More, With Dr. Gabrielle Lyon
Your Butt is a Longevity Organ (Here’s how to train it!) | Gabrielle Lyon
Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.













