6-Step Protocol To Stop Decline, Stay Young & Reverse Aging After 40+
Mark Hyman
May 24, 2024
Mindsip insights from this episode:
Utilize plasma exchange to reverse biological age
Plasma exchange, a process of cleaning your blood by removing old plasma and its inflammatory components, may have the most significant impact on reversing biological age.
Reverse biological age with plant-rich, keto-leaning diet in eight weeks
A groundbreaking study showed that a plant-rich, keto-leaning diet with exercise and supplements reversed biological age by an average of 3.23 years in just eight weeks.
Leverage plant stress to activate healing pathways
The principle of phytohormesis suggests that small, non-lethal doses of plant toxins, like those in cruciferous vegetables, beneficially stress your body to activate healing and anti-inflammatory pathways.
Implement time-restricted eating to influence gene expression
Research from the Salk Institute found that time-restricted eating affects the expression of approximately 70% of genes, influencing hormones and activating anti-aging pathways like autophagy.
Reduce biological age by 1.85 years with daily vitamin D3 intake
Taking 4,000 units of vitamin D3 daily, with no other changes, was shown in one study to reduce biological age by 1.85 years in just 16 weeks.
Supplement with fisetin to eliminate zombie cells and reduce inflammation
Fisetin, a phytochemical from strawberries, can be supplemented at 500-1000 milligrams to help kill inflammatory senescent "zombie cells" that accumulate with age.
Supplement with urolithin A to enhance mitochondrial health
Urolithin A, a postbiotic made from pomegranates by gut bacteria, can be supplemented with a product called Mitopure to improve mitochondrial health.
Utilize peptides BPC-157 and Thymosin Alpha-1 for healing and immunity
Specific peptides like BPC-157 and Thymosin Alpha-1 are emerging regenerative therapies that can be used to help with healing and immunity.
More from
Mark Hyman
From Drug Smuggler to Healer: How Nick Brewer Created Primal Moves
The Silent Fire Behind Chronic Disease—and How to Put It Out
One Dose That Heals Addiction, PTSD, and Brain Injury? Dr. Nolan Williams on The Science of Ibogaine
The Nutrient Blueprint for a Longer, Healthier Life
The Biohacks Ben Greenfield No Longer Uses (and What He Does Instead)
You also might be interested in
Food & Supplements for Brain Health & Cognitive Performance | Huberman Lab Essentials
I Read 500 Studies: 10 Things I Learned about your Health
Low-Carb Vs. High-Carb Battle — What's BETTER For Your Health & Metabolism: Fats or Sugar? with Dr. Eric Westman and Jay Feldman
Brain Expert: 'If You Have Brain Fog, Fatigue or Burnout — It Might Be Your Eyes!' | Bryce Appelbaum
The Most Underrated Exercise for Overall Health & Performance
