Are We Wrong About the Perfect Protein Intake?

Brad Stanfield

Jul 28, 2025

Episode description

For weekly health research summaries and extra insights, sign up here 👉 https://drstanfield.com/pages/sign-up

💊 Supplements I Take: https://drstanfield.com/pages/my-supplements

💊MicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus
💊MicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin

📜 Roadmap - how to look young & feel strong: https://drstanfield.com/pages/roadmap

Timestamps
0:00 Dr Valter Longo's Compelling Case for a Low-Protein Diet
3:46 Important Qualifications: Protein Source and Age
5:38 The Balancing Act: Addressing Muscle Loss (Sarcopenia)
9:42 Optimal Protein for Muscle Gains and Weight Management
11:02 Addressing Kidney Health Concerns
12:17 Protein & Cancer
13:05 Plant vs Animal Protein
14:28 Your Optimal Protein Intake & How to Calculate It

✔️ Twitter: https://twitter.com/BradStanfieldMD
✔️ Patreon: https://www.patreon.com/bradstanfieldmd

Here are the links to the research papers referenced in the video:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3988204/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5872778/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6442923/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5867436/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7727026/
https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
https://pmc.ncbi.nlm.nih.gov/articles/PMC7539343/
https://pubmed.ncbi.nlm.nih.gov/17299116/
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822055
https://pmc.ncbi.nlm.nih.gov/articles/PMC11329548/
https://www.nature.com/articles/s41598-023-30455-9
https://pmc.ncbi.nlm.nih.gov/articles/PMC7374797/
https://www.sciencedirect.com/science/article/pii/S026156142030251X
https://www.mdcalc.com/calc/68/ideal-body-weight-adjusted-body-weight

Thumbnail by James Kelly
Video edited by Troy Young
Script by John Milliken

The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Episode description

For weekly health research summaries and extra insights, sign up here 👉 https://drstanfield.com/pages/sign-up

💊 Supplements I Take: https://drstanfield.com/pages/my-supplements

💊MicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus
💊MicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin

📜 Roadmap - how to look young & feel strong: https://drstanfield.com/pages/roadmap

Timestamps
0:00 Dr Valter Longo's Compelling Case for a Low-Protein Diet
3:46 Important Qualifications: Protein Source and Age
5:38 The Balancing Act: Addressing Muscle Loss (Sarcopenia)
9:42 Optimal Protein for Muscle Gains and Weight Management
11:02 Addressing Kidney Health Concerns
12:17 Protein & Cancer
13:05 Plant vs Animal Protein
14:28 Your Optimal Protein Intake & How to Calculate It

✔️ Twitter: https://twitter.com/BradStanfieldMD
✔️ Patreon: https://www.patreon.com/bradstanfieldmd

Here are the links to the research papers referenced in the video:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3988204/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5872778/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6442923/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5867436/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7727026/
https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
https://pmc.ncbi.nlm.nih.gov/articles/PMC7539343/
https://pubmed.ncbi.nlm.nih.gov/17299116/
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822055
https://pmc.ncbi.nlm.nih.gov/articles/PMC11329548/
https://www.nature.com/articles/s41598-023-30455-9
https://pmc.ncbi.nlm.nih.gov/articles/PMC7374797/
https://www.sciencedirect.com/science/article/pii/S026156142030251X
https://www.mdcalc.com/calc/68/ideal-body-weight-adjusted-body-weight

Thumbnail by James Kelly
Video edited by Troy Young
Script by John Milliken

The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Mindsip insights from this episode:

Avoid one week of bedrest to preserve muscle mass

Even if you are healthy and eating normally, one week of bedrest can cause the loss of approximately 1.4 kg (over 3 lbs) of muscle mass.

Limit high-protein diets to reduce cancer risk

In adults aged 50-65, a high-protein diet was linked to a 74% higher risk of all-cause mortality and a four-fold increased risk of dying from cancer.

Limit animal protein to improve health outcomes

The negative health effects of high protein intake were primarily associated with animal protein, whereas plant-based protein was not found to be a problem.

Increase protein intake after 65 to reduce cancer risk and frailty

After age 65, the negative associations with high protein reverse, and a higher intake becomes beneficial for reducing cancer mortality and frailty.

Understand muscle loss occurs in rapid bursts during inactivity

The 'catabolic crisis model' proposes that we lose muscle not gradually, but in rapid bursts during short periods of inactivity or illness, which we don't fully regain.

Set optimal protein target at 1.2g per kilogram of ideal body weight

After reviewing all the evidence, the speaker recommends a new optimal protein target of 1.2g per kilogram of ideal body weight, which is lower than many popular recommendations.

Increase protein intake to lower mortality in kidney disease

Contrary to common advice, a recent study showed that patients with mild to moderate chronic kidney disease had 33% lower mortality with a higher protein intake.

Incorporate pea protein for cancer prevention and longevity

The speaker personally uses pea protein powder because it is plant-based and low in the amino acid methionine, which has been linked to cancer growth.

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