Cardiac Preconditioning: How to Use Mini Heart Attacks to protect against Heart Attacks

Physionic

Jan 22, 2025

Episode description

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0:00 - Introduction
0:35 - Ischemic Heart Attack
1:05 - The Impact of Cardiac Preconditioning
1:52 - Understanding Preconditioning
2:30 - How does Cardiac Preconditioning work?
4:26 - How to increase Cardiac Preconditioning?
5:49 - A Caveat...

References
[Study 390] Zaugg M, Lucchinetti E, Uecker M, Pasch T, Schaub MC. Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms. Br J Anaesth. 2003;91(4):551-565. doi:10.1093/bja/aeg205

Funding/Conflicts: Non-Profit Funding [Swiss Society for Anaesthesiology and Perioperative Medicine; Swiss National Science Foundation; Hartmann-Miller Foundation; Swiss Heart Foundation] / Unknown Conflicts of Interest

[Study 391] Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart. J Appl Physiol (1985). 2011;111(3):905-915. doi:10.1152/japplphysiol.00004.2011

Funding/Conflicts: Unknown Funding / No Conflicts of Interest

********CRITIQUES, RULES, AND NOTES********

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Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

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If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

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Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#hearthealthtips #hearthealthawareness

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:35 - Ischemic Heart Attack
1:05 - The Impact of Cardiac Preconditioning
1:52 - Understanding Preconditioning
2:30 - How does Cardiac Preconditioning work?
4:26 - How to increase Cardiac Preconditioning?
5:49 - A Caveat...

References
[Study 390] Zaugg M, Lucchinetti E, Uecker M, Pasch T, Schaub MC. Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms. Br J Anaesth. 2003;91(4):551-565. doi:10.1093/bja/aeg205

Funding/Conflicts: Non-Profit Funding [Swiss Society for Anaesthesiology and Perioperative Medicine; Swiss National Science Foundation; Hartmann-Miller Foundation; Swiss Heart Foundation] / Unknown Conflicts of Interest

[Study 391] Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart. J Appl Physiol (1985). 2011;111(3):905-915. doi:10.1152/japplphysiol.00004.2011

Funding/Conflicts: Unknown Funding / No Conflicts of Interest

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#hearthealthtips #hearthealthawareness

Mindsip insights from this episode:

Utilize cardiac preconditioning to prevent major heart attacks

Cardiac preconditioning involves inducing short periods of ischemia, similar to a mini-heart attack, to create lasting protection against a future, major heart attack.

Exercise every other day for continuous heart protection

The heart conditioning effects from exercise can last up to 72 hours, meaning exercising every other day could provide constant protection.

Utilize preconditioning within 40 minutes for maximum protection

The protective effect of preconditioning is time-sensitive; in one animal study, it significantly reduced damage within a 40-minute window but offered no protection after three hours.

Increase BCL2 protein to block heart cell death through preconditioning

One way preconditioning works is by increasing the BCL2 protein, which blocks a form of programmed cell death called apoptosis in heart muscle cells.

Implement cardiac preconditioning to reduce heart attack size by 40%

Cardiac preconditioning is a technique that can reduce the size of a future heart attack by 40% or more, which could be the difference between life and death.

Induce cardiac preconditioning through aerobic endurance exercise

Aerobic endurance exercise, and possibly high-intensity interval training, is a practical way to induce cardiac preconditioning and its protective effects.

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