Control Pain & Heal Faster With Your Brain | Huberman Lab Essentials

Andrew Huberman

Jan 9, 2025

Episode description

In this Huberman Lab Essentials episode, I explain how to manage pain and accelerate injury recovery by leveraging protocols to modulate pain perception.

I discuss how pain interpretation is a complex experience, shaped by both internal factors like emotions and genetics, as well as external factors, such as context. I explain how practical strategies like acupuncture, breathing techniques, exercise and temperature modulation can influence the body’s pain response and accelerate recovery. I also discuss topics like phantom limb pain, recovering from traumatic brain injury and the crucial role inflammation plays in the healing process.

Episode show notes: https://go.hubermanlab.com/xYRBZIy

Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch or listen to the full-length episode: https://youtu.be/mcPSRWUYCv0

*Timestamps*
00:00:00 Huberman Lab Essentials; Neuroplasticity
00:01:58 Somatosensory System, Pain
00:05:22 Pain & Injury; Genes
00:07:38 Touch, Sensitivity, Pain, Inflammation
00:09:53 Phantom Limb Pain, Top-Down Modulation
00:14:00 Traumatic Brain Injury, Aging & Glymphatic System; Tools: Side Sleeping, Zone 2 Cardio
00:19:05 Pain Interpretation, Adrenaline, Emotion & Love
00:22:19 Acupuncture; Homunculus, Somatosensory System, Gut & Inflammation
00:29:31 Tool: Wim Hof Method, Tummo Breathing, Pain
00:30:29 Tools: Injury Management, Ice or Heat?
00:34:10 Platelet-Rich Plasma (PRP), Stem Cells
00:35:43 Recap & Key Takeaways

Disclaimer & Disclosures:: https://www.hubermanlab.com/disclaimer

Episode description

In this Huberman Lab Essentials episode, I explain how to manage pain and accelerate injury recovery by leveraging protocols to modulate pain perception.

I discuss how pain interpretation is a complex experience, shaped by both internal factors like emotions and genetics, as well as external factors, such as context. I explain how practical strategies like acupuncture, breathing techniques, exercise and temperature modulation can influence the body’s pain response and accelerate recovery. I also discuss topics like phantom limb pain, recovering from traumatic brain injury and the crucial role inflammation plays in the healing process.

Episode show notes: https://go.hubermanlab.com/xYRBZIy

Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch or listen to the full-length episode: https://youtu.be/mcPSRWUYCv0

*Timestamps*
00:00:00 Huberman Lab Essentials; Neuroplasticity
00:01:58 Somatosensory System, Pain
00:05:22 Pain & Injury; Genes
00:07:38 Touch, Sensitivity, Pain, Inflammation
00:09:53 Phantom Limb Pain, Top-Down Modulation
00:14:00 Traumatic Brain Injury, Aging & Glymphatic System; Tools: Side Sleeping, Zone 2 Cardio
00:19:05 Pain Interpretation, Adrenaline, Emotion & Love
00:22:19 Acupuncture; Homunculus, Somatosensory System, Gut & Inflammation
00:29:31 Tool: Wim Hof Method, Tummo Breathing, Pain
00:30:29 Tools: Injury Management, Ice or Heat?
00:34:10 Platelet-Rich Plasma (PRP), Stem Cells
00:35:43 Recap & Key Takeaways

Disclaimer & Disclosures:: https://www.hubermanlab.com/disclaimer

Mindsip insights from this episode:

Sleep on your side to enhance brain clearance

Sleeping on your side, rather than your back or stomach, appears to increase the clearance of cellular debris by the brain's glymphatic system.

Reframe pain as a belief system to transform perception

Pain is a perceptual experience as much as a physical one, meaning it's a belief system about what you are experiencing in your body.

Utilize love to reduce pain response

Looking at an image of a romantic partner you love can significantly blunt the pain response, an effect that is especially strong in new relationships.

Recognize acute inflammation as vital for healing

Acute inflammation is a beneficial and essential response that calls cells to the site of an injury to clean it up and allow for healing.

Ditch ice, use heat to enhance injury recovery

Icing an injury is largely a placebo for pain and can slow healing by creating tissue 'sludging,' whereas heat is often more beneficial for improving fluid clearance.

Engage in Zone 2 cardio to enhance brain health

Performing Zone 2 cardio for 30-45 minutes three times a week can improve the function of the brain's glymphatic clearance system, supporting brain health.

Exercise caution with stem cell therapies due to risks

Stem cell therapies like PRP have feeble evidence for their claims and carry the risk of cells becoming tumors, so they should be approached with extreme caution.

Utilize Wim Hof breathing to release adrenaline and reduce pain

The pain-blunting effect of Wim Hof-style breathing is not mysterious; it works by liberating adrenaline from the adrenal glands.

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© Mindsip 2025 – Made with ❤ in Vilnius