Fatty Liver Is the New Smoking—And 90 Million Americans Have It
Mark Hyman
Apr 7, 2025
Mindsip insights from this episode:
Address SIBO to prevent liver toxicity
Small intestinal bacterial overgrowth (SIBO) can cause bacteria to ferment food and release toxic metabolites that directly poison your liver.
Incorporate NAC, lipoic acid, and milk thistle to heal your liver
Key supplements for healing the liver include N-acetylcysteine (NAC) to boost glutathione, lipoic acid, and milk thistle.
Motivate lifestyle changes by addressing liver health
Patients are often more motivated to change their lifestyle when told they have a liver problem than when warned about a future heart attack.
Get accurate cholesterol assessment with lipoprotein fractionation test
Less than 1% of cholesterol tests are the right kind; you need a lipoprotein fractionation test to see the dangerous small, dense particles caused by fatty liver.
Eliminate high-fructose corn syrup for liver health
The single most impactful dietary change you can make is to avoid every food product with high-fructose corn syrup, as it is uniquely toxic to the liver.
Recognize fat as an active endocrine organ affecting insulin resistance
Your fat is an active endocrine organ that produces inflammatory hormones like tumor necrosis factor and can worsen insulin resistance.
Recognize bagels as sugary foods to protect liver health
From a metabolic perspective, your body cannot tell the difference between a bagel and a soda, as both sugary and starchy foods drive fatty liver.
Recognize insulin resistance in healthy-looking young men
A study on young, normal-weight men in their 20s found that more than half of them already had insulin resistance.
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