How Your Appetite Is Affected By Your Hormones

Mark Hyman

Jan 26, 2024

Episode description

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Our hormones coordinate many different functions in our body and control everything from our metabolism to our sexual function, circadian rhythms, and mood. These chemical messengers also play a big role when it comes to our appetites.



In today’s episode of my series I’m calling Health Bites, I am talking about two lesser-known hormones, leptin and ghrelin, which you may not have heard of before but that have a direct impact on our body and health. 



This episode is brought to you by Mitopure, Rupa Health, and Seed.



Support essential mitochondrial health and save 30% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN30.



Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com today.



Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.



In this episode, I discuss (audio version / Apple Subscriber version):

  • Why are so many people overweight? (3:29 / 1:36)

  • What do leptin and ghrelin regulate in our bodies? (4:20 / 2:27)

  • What happens when your leptin and ghrelin levels are out of whack? (6:27 / 4:35)

  • Strategies to keep your leptin and ghrelin levels balanced and healthy (12:02 / 8:46)



Mentioned in this episode

The Fat Resistance Diet by Dr. Leo Galland

Force of Nature

FOOD: What the Heck Should I Eat?





Episode description

View the Show Notes For This Episode



Get Free Weekly Health Tips from Dr. Hyman



Sign Up for Dr. Hyman’s Weekly Longevity Journal



Get Ad-free Episodes & Dr. Hyman+ Audio Exclusives



Our hormones coordinate many different functions in our body and control everything from our metabolism to our sexual function, circadian rhythms, and mood. These chemical messengers also play a big role when it comes to our appetites.



In today’s episode of my series I’m calling Health Bites, I am talking about two lesser-known hormones, leptin and ghrelin, which you may not have heard of before but that have a direct impact on our body and health. 



This episode is brought to you by Mitopure, Rupa Health, and Seed.



Support essential mitochondrial health and save 30% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN30.



Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com today.



Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.



In this episode, I discuss (audio version / Apple Subscriber version):

  • Why are so many people overweight? (3:29 / 1:36)

  • What do leptin and ghrelin regulate in our bodies? (4:20 / 2:27)

  • What happens when your leptin and ghrelin levels are out of whack? (6:27 / 4:35)

  • Strategies to keep your leptin and ghrelin levels balanced and healthy (12:02 / 8:46)



Mentioned in this episode

The Fat Resistance Diet by Dr. Leo Galland

Force of Nature

FOOD: What the Heck Should I Eat?





Mindsip insights from this episode:

Manage sleep to control hunger and cravings

Studies on sleep-deprived students found they had higher levels of the hunger hormone ghrelin, which made them hungrier and specifically crave more carbs and sugar.

Incorporate HIIT to enhance leptin sensitivity and control appetite

High-Intensity Interval Training (HIIT) is a particularly effective form of exercise for improving leptin sensitivity, which helps your body better recognize signals to stop eating.

Recognize environmental factors influencing appetite regulation

People are victims of an environment that drives their hormones in the wrong direction, making them unable to regulate their appetite and hunger.

Limit ultra-processed foods to regulate appetite and reduce overeating

An NIH study showed that people on an unlimited ultra-processed food diet ate 500 more calories per day because these foods dysregulate appetite hormones.

Revitalize mitochondria with Mitopure for age-related fatigue

The supplement Mitopure, containing Urolithin A, is mentioned to fight age-related fatigue at the source by giving cellular powerhouses, the mitochondria, a new life.

Avoid late-night eating to regulate next-day appetite

A Harvard study found that late-night eating decreases leptin levels for the next 24 hours, effectively turning off the 'brake' on your appetite for the entire following day.

Reduce belly fat to combat leptin resistance and hunger

Visceral belly fat actively produces inflammatory molecules called adipocytokines that travel to your brain and cause leptin resistance, making you feel hungry even when you're not.

Utilize Seed DSO1 probiotic for gut and cellular health

The Seed DSO1 probiotic contains a pomegranate-derived prebiotic that your gut bacteria transform into beneficial metabolites like urolithins, which support cellular health.

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