
It’s Not a Stroke — It’s Your Arteries Slowly Attacking your Brain
Physionic
Nov 24, 2025
Mindsip insights from this episode:
Protect brain's communication pathways from plaque damage
The attack on the brain results in white matter lesions, which is damage to the protective myelin sheath that insulates your brain's communication pathways.
Address trapped immune cells to combat arterial plaque damage
The damaging messages originate from your own immune cells that become overburdened with cholesterol in arterial plaque, turning into 'foam cells.'.
Recognize plaque's harmful exosomes traveling to the brain
Plaque in your arteries releases tiny packages called exosomes, which travel through the body to the brain to deliver their harmful message.
Protect brain's immune cells from exosome hijacking
Exosomes from arterial plaque don't cause damage directly, but instead hijack the brain's own immune cells, called microglia, causing them to become destructive.
Reduce plaque to prevent brain cell inflammation
Exosomes from plaque cause brain immune cells to increase the production of pro-inflammatory molecules and reduce the activity of their mitochondria.
Protect your brain from arterial plaque damage
Arterial plaque actively harms your brain by sending out damaging messages, even when the plaque is not located in arteries near your brain.
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