Nattokinase: Plaque Reversing Supplement, or Biased Science?

Physionic

Jun 10, 2024

Episode description

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Created with Biorender

Full Analysis: https://youtu.be/Jv6flHrh0NQ

References [Copy & Paste DOI into Search Engine]
[1] doi:10.3390/nu15194239
[2] doi:10.2147/IBPC.S99553
[3] doi:10.1291/hypres.31.1583
[4] doi:10.3389/fcvm.2022.964977
[5] doi:10.1089/jmf.2019.0183
[6] Lipid-Lowering Effect of Nattokinase in Patients with Primary Hypercholesterolemia (No DOI)
[7] doi.org/10.3233/CH-211147
[8] doi:10.1039/c8fo02324g
[9] PMID: 19786378

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#nattokinase #heartdiseaseprevention #heartdiseasetreatment

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H


Created with Biorender

Full Analysis: https://youtu.be/Jv6flHrh0NQ

References [Copy & Paste DOI into Search Engine]
[1] doi:10.3390/nu15194239
[2] doi:10.2147/IBPC.S99553
[3] doi:10.1291/hypres.31.1583
[4] doi:10.3389/fcvm.2022.964977
[5] doi:10.1089/jmf.2019.0183
[6] Lipid-Lowering Effect of Nattokinase in Patients with Primary Hypercholesterolemia (No DOI)
[7] doi.org/10.3233/CH-211147
[8] doi:10.1039/c8fo02324g
[9] PMID: 19786378

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#nattokinase #heartdiseaseprevention #heartdiseasetreatment

Mindsip insights from this episode:

Utilize nattokinase for lowering high blood pressure only

Nattokinase supplementation appears to lower blood pressure only in individuals with pre-existing high blood pressure, showing no effect in those with normal levels.

Understand nattokinase as a protease for blood clot management

Despite its name, nattokinase is not a kinase enzyme but a protease, meaning it works by degrading proteins like the fibrin that holds blood clots together.

Utilize high-dose nattokinase to reverse atherosclerosis

A study using a high dose of nattokinase (11,000 FU) reported an impressive 21% reversal of atherosclerosis in just over one year.

Critique flawed pro-nattokinase study on plaque reversal

The study showing significant plaque reversal is scientifically questionable because it lacked a control group and had potential industry conflicts of interest.

Reevaluate nattokinase dosage for atherosclerosis management

In a well-controlled study, a typical low dose of nattokinase (2,000 FU) taken for three years did not reverse or slow atherosclerosis compared to a placebo.

Determine specific dosages for atherosclerosis treatment

The studies on atherosclerosis used a low dose of 2,000 fibrinolytic units (FU) and a high dose of almost 11,000 FU.

Dismiss nattokinase as a cholesterol-lowering tool

Across multiple studies, nattokinase showed no effect on lipoprotein particle numbers, suggesting it is not an effective tool for lowering cholesterol carriers.

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