
Nattokinase: Plaque Reversing Supplement, or Biased Science?
Physionic
Jun 10, 2024
Mindsip insights from this episode:
Utilize nattokinase for lowering high blood pressure only
Nattokinase supplementation appears to lower blood pressure only in individuals with pre-existing high blood pressure, showing no effect in those with normal levels.
Understand nattokinase as a protease for blood clot management
Despite its name, nattokinase is not a kinase enzyme but a protease, meaning it works by degrading proteins like the fibrin that holds blood clots together.
Utilize high-dose nattokinase to reverse atherosclerosis
A study using a high dose of nattokinase (11,000 FU) reported an impressive 21% reversal of atherosclerosis in just over one year.
Critique flawed pro-nattokinase study on plaque reversal
The study showing significant plaque reversal is scientifically questionable because it lacked a control group and had potential industry conflicts of interest.
Reevaluate nattokinase dosage for atherosclerosis management
In a well-controlled study, a typical low dose of nattokinase (2,000 FU) taken for three years did not reverse or slow atherosclerosis compared to a placebo.
Determine specific dosages for atherosclerosis treatment
The studies on atherosclerosis used a low dose of 2,000 fibrinolytic units (FU) and a high dose of almost 11,000 FU.
Dismiss nattokinase as a cholesterol-lowering tool
Across multiple studies, nattokinase showed no effect on lipoprotein particle numbers, suggesting it is not an effective tool for lowering cholesterol carriers.
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