
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Andrew Huberman
Nov 24, 2025
Mindsip insights from this episode:
Recognize high AMH as a potential PCOS indicator
Contrary to popular belief, a very high AMH (egg count) can be a sign of PCOS and poor egg quality, not superior fertility.
Recognize connection between PCOS and endometriosis for better diagnosis
Dr. Aliabadi hypothesizes that over 50% of patients with PCOS also suffer from endometriosis, a connection often missed by doctors.
Recognize recurrent UTI symptoms as potential endometriosis indicator
Experiencing recurrent bladder or UTI-like symptoms that consistently result in negative cultures is a major red flag for endometriosis.
Utilize pulsatile SSRIs for effective PMDD management
For PMDD, antidepressants like Prozac or Zoloft can be taken in a 'pulsatile' manner for just 10-14 days a month and still be highly effective.
Recognize estrogen withdrawal bleeding as non-ovulatory period
Many women with PCOS experience regular bleeding that they believe is a period, but it's often just estrogen withdrawal bleeding as they are not actually ovulating.
Utilize Tyrer-Cuzick tool to assess breast cancer risk
Every woman should use the free Tyrer-Cuzick risk assessment tool to calculate her lifetime risk of breast cancer, as this number dictates screening protocols.
Consider SLYND for PCOS management due to anti-androgenic effects
The progesterone-only birth control pill SLYND is a good option for some PCOS patients because it is anti-androgenic.
Take free online PCOS assessment at OVI.com
A free online quiz at OVI.com, created by Dr. Aliabadi, can help women assess their likelihood of having PCOS.
Start annual breast imaging at 30 if lifetime risk is 20% or more
If your lifetime breast cancer risk is 20% or more, you qualify for annual breast imaging starting at age 30, not the standard age of 40.
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