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Nutrition isn't Enough - Add This: https://www.youtube.com/watch?v=hypkeQ3FL4Q&t=2s

0:00 - Introduction
0:24 - Insulin Resistance: A Matter of Time of Day
2:19 - Liver… STOP!
3:34 - Pancreas: What happened to You??
5:10 - A Major Take-Away

References
[Study 706] Marjot T, Smith K, Westcott F, et al. Human MASLD is a diurnal disease driven by multisystem insulin resistance and reduced insulin availability at night. Cell Metab. 2026;38(3):474-492. doi:10.1016/j.cmet.2025.12.004

Funding/Conflict: Public Funding: From the study, support was reported from the NIHR Oxford Biomedical Research Centre, the Oxford Health Biomedical Research Centre – Better Sleep Theme, and the Medical Research Council of Australia, including Investigator Grant 2009642 to B.L.P.; Non-Profit Funding: From the study, no non-profit funding was reported; Industry Funding: From the study, no industry funding was reported; Conflicts of Interest: From the study, the authors declared no competing interests.

[Study 707] Moholdt T, Parr EB, Devlin BL, et al. The effect of morning vs evening exercise training on glycaemic control and serum metabolites in overweight/obese men: a randomised trial. Diabetologia. 2021;64(9):2061-2076. doi:10.1007/s00125-021-05477-5

Funding/Conflict: Public Funding: From the study, this research was supported by a Mobility Grant from The Liaison Committee for Education, Research and Innovation in Central Norway (2016/29014) to TM; Non-Profit Funding: From the study, this research was also supported by a Novo Nordisk Foundation Challenge Grant (NNF14OC0011493) to JAH; Industry Funding: From the study, no industry funding was reported; Conflicts of Interest: From the study, the authors declared that there were no relationships or activities that might bias, or be perceived to bias, their work.

[Study 708] Savikj M, Gabriel BM, Alm PS, et al. Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial. Diabetologia. 2019;62(2):233-237. doi:10.1007/s00125-018-4767-z

Funding/Conflict: Public Funding: From the study, the authors were supported by the Swedish Research Council (2015-00165), the Strategic Research Program in Diabetes at Karolinska Institutet (2009-1068), and Stockholm County Council (SLL20150517 and SLL20170159); Non-Profit Funding: From the study, support was also reported from the Novo Nordisk Foundation (NNF14OC0011493 and NNF14OC0009941), the Swedish Diabetes Foundation (DIA2015-052), the Wenner-Gren Foundation, and the Swedish Heart Lung Foundation (20150423); Industry Funding: From the study, no industry funding was reported; Conflicts of Interest: From the study, the authors declared that there was no duality of interest associated with the manuscript.

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