Preventing Dementia: It only takes ONE Workout per Week!

Physionic

Nov 10, 2025

Episode description

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0:00 - Introduction
1:02 - 'Weekend Warrior' vs Dementia
6:43 - Main Points

VILPA video linked at the end: https://youtu.be/w5IN0WrPEHw

References
[Study 540] Min J, Cao Z, Duan T, Wang Y, Xu C. Accelerometer-derived “weekend warrior” physical activity pattern and brain health. Nat Aging. 2024;4(10):1394-1402. doi:10.1038/s43587-024-00688-y

Funding/Conflicts: This study was supported by several funding sources, including the National Natural Science Foundation of China (Grant Nos. ​ 72204071 to Chenjie Xu and 72342017 to Yaogang Wang), the Zhejiang Provincial Natural Science Foundation of China (Grant No. ​ LY23G030005 to Chenjie Xu), the Major Science and Technology Project of Public Health in Tianjin (Grant No. ​ 21ZXGWSY00090 to Yaogang Wang), and the Scientific Research Foundation for Scholars of Hangzhou Normal University (Grant No. ​ 4265C50221204119 to Chenjie Xu). The authors have declared that they have no competing interests. ​

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
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Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
1:02 - 'Weekend Warrior' vs Dementia
6:43 - Main Points

VILPA video linked at the end: https://youtu.be/w5IN0WrPEHw

References
[Study 540] Min J, Cao Z, Duan T, Wang Y, Xu C. Accelerometer-derived “weekend warrior” physical activity pattern and brain health. Nat Aging. 2024;4(10):1394-1402. doi:10.1038/s43587-024-00688-y

Funding/Conflicts: This study was supported by several funding sources, including the National Natural Science Foundation of China (Grant Nos. ​ 72204071 to Chenjie Xu and 72342017 to Yaogang Wang), the Zhejiang Provincial Natural Science Foundation of China (Grant No. ​ LY23G030005 to Chenjie Xu), the Major Science and Technology Project of Public Health in Tianjin (Grant No. ​ 21ZXGWSY00090 to Yaogang Wang), and the Scientific Research Foundation for Scholars of Hangzhou Normal University (Grant No. ​ 4265C50221204119 to Chenjie Xu). The authors have declared that they have no competing interests. ​

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Mindsip insights from this episode:

Use talk test to gauge exercise intensity

You are likely exercising at the correct moderate-to-vigorous intensity if your heart rate is elevated and it becomes difficult to talk while active.

Recognize yard work as effective exercise for dementia protection

Physical activity is a broad term that includes manual labor like yard work or construction, which counts towards dementia protection, not just traditional exercise.

Limit physical activity to 115 minutes weekly for dementia protection

Doing more than 115 minutes of total physical activity per week does not provide any additional dementia protection benefits.

Maximize brain health with weekend warrior workouts

Stuffing the majority of your weekly physical activity into one or two sessions is just as protective for brain health as spreading it out over many sessions.

Prioritize total physical activity time to reduce dementia risk

For reducing dementia risk, the total time spent being physically active is more important than the number of times you are active per week.

Maximize dementia protection with one weekly session of physical activity

Even when the majority of your 115 minutes of weekly physical activity is lumped into a single session, it provides an equal amount of dementia protection.

Engage in 115 minutes of activity weekly to cut dementia risk

As little as 115 minutes of moderate-to-vigorous physical activity per week is enough to achieve a 23% reduction in dementia risk.

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