The Hidden Seed Oil Study that was Supposed to Change Everything

Physionic

Jun 18, 2025

Episode description

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*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

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Created with Biorender

Original Video: https://www.youtube.com/watch?v=7SFpGVIds14&t=5s

0:00 - Introduction
0:59 - The Buried Study
3:01 - Seed Oils (Unsaturated Fats) increase Death Risk over Saturated Fats
4:08 - A Major Critique!
7:28 - Nuances.. or Truth?
12:40 - Chasing Down Buried Data - A Crazy Story!
14:35 - Main Points

References
[Study 475] Woodhill JM, Palmer AJ, Leelarthaepin B, McGilchrist C, Blacket RB. Low fat, low cholesterol diet in secondary prevention of coronary heart disease. In: Kritchevsky D, ed. Drugs, Lipid Metabolism, and Atherosclerosis. New York, NY: Plenum Press; 1978:317-330.

Funding/Conflicts: Internal Funding [Department of Medicine, University of New South Wales, at Prince Henry Hospital, Little Bay, Australia] // No direct Conflicts of Interest

[Study 476] Ramsden CE, Zamora D, Leelarthaepin B, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707. doi:10.1136/bmj.e8707.

Funding/Conflicts: Public Funding [Intramural Research Program of the National Institutes of Health (NIH), National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute on Aging (NIA)] / No direct Conflicts of Interest

[A] https://www.bmj.com/content/346/bmj.e8707/rr/629609

[B] https://www.ausfoodnews.com.au/2013/02/11/heart-foundation-takes-swipe-at-butter-and-new-study-on-margarine.html#:~:text=Replacing%20saturated%20fat%20with%20a,studies%20of%20a%20similar%20kind.

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

Original Video: https://www.youtube.com/watch?v=7SFpGVIds14&t=5s

0:00 - Introduction
0:59 - The Buried Study
3:01 - Seed Oils (Unsaturated Fats) increase Death Risk over Saturated Fats
4:08 - A Major Critique!
7:28 - Nuances.. or Truth?
12:40 - Chasing Down Buried Data - A Crazy Story!
14:35 - Main Points

References
[Study 475] Woodhill JM, Palmer AJ, Leelarthaepin B, McGilchrist C, Blacket RB. Low fat, low cholesterol diet in secondary prevention of coronary heart disease. In: Kritchevsky D, ed. Drugs, Lipid Metabolism, and Atherosclerosis. New York, NY: Plenum Press; 1978:317-330.

Funding/Conflicts: Internal Funding [Department of Medicine, University of New South Wales, at Prince Henry Hospital, Little Bay, Australia] // No direct Conflicts of Interest

[Study 476] Ramsden CE, Zamora D, Leelarthaepin B, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707. doi:10.1136/bmj.e8707.

Funding/Conflicts: Public Funding [Intramural Research Program of the National Institutes of Health (NIH), National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute on Aging (NIA)] / No direct Conflicts of Interest

[A] https://www.bmj.com/content/346/bmj.e8707/rr/629609

[B] https://www.ausfoodnews.com.au/2013/02/11/heart-foundation-takes-swipe-at-butter-and-new-study-on-margarine.html#:~:text=Replacing%20saturated%20fat%20with%20a,studies%20of%20a%20similar%20kind.

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Mindsip insights from this episode:

Adjust for physical activity in seed oil analysis to improve survival predictions

The newer analysis that found negative effects from seed oils failed to adjust for physical activity, which the original study identified as highly predictive of survival.

Clarify misconceptions about buried study data retrieval

The reanalysis team did not find the 'buried' study data in a basement; they simply requested it from one of the original authors who provided it.

Highlight low trans fat content in Miracle brand margarine to challenge study findings

A key argument against the study's negative findings is that the Miracle brand soft margarine used had very little, if any, trans fats compared to hard margarines.

Question margarine claims: investigate trans fat content

Contrary to claims, nutrition researchers at the time estimated that Miracle brand margarine likely contained a significant amount of trans fats.

Avoid seed oils to reduce death risk by 62%

The Sydney Diet Heart Study concluded that replacing saturated fat with polyunsaturated fats from seed oils increased the risk of death by 62%.

Clarify dietary impacts by eliminating margarine in studies

The study's results were muddied because both the seed oil group and the control group were allowed to consume margarine, making the dietary differences smaller than intended.

Recognize non-dietary factors as key mortality predictors

The original study found that factors like medication use, diabetes, and even divorce were more predictive of mortality than the dietary changes.

Critique Sydney Heart trial for flawed conclusions on seed oils

The Sydney Heart trial was confounded by multiple factors and is not a reliable basis to either accept or refute the health effects of seed oils.

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