The Power of the Mediterranean Diet: Reversing Atherosclerosis

Physionic

Mar 24, 2025

Episode description

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0:00 - Introduction
0:20 - Study Background
1:24 - Reversing Atherosclerosis
2:05 - Why the Mediterranean Diet?
3:30 - Heart Attack Risk?
4:06 - How does this happen?
4:43 - Main Point

References
[Study 424] Jimenez-Torres J, Alcalá-Diaz JF, Torres-Peña JD, et al. Mediterranean Diet Reduces Atherosclerosis Progression in Coronary Heart Disease: An Analysis of the CORDIOPREV Randomized Controlled Trial [published correction appears in Stroke. 2021 Nov;52(11):e754. doi: 10.1161/STR.0000000000000393.]. Stroke. 2021;52(11):3440-3449. doi:10.1161/STROKEAHA.120.033214

Funding/Conflicts: Public [Fundación Patrimonio Comunal Olivarero; Consejería de Economía, Innovación, Ciencia y Empleo; Ministerio de Ciencia e Innovación; Spanish Society of Atherosclerosis; Instituto de Salud Carlos III (ISCIII) of Spain; Directorate General for Assessment and Promotion of Research and the EU’s European Regional Development Fund (FEDER); Servicio Andaluz de Salud, Junta de Andalucia, Spain] // Potential Conflicts of Interest [Dr. Alcalá-Diaz is paid by Bayer, Grunenthal Pharma, Esteve, Ferrer, and Boehringer Ingelheim; Dr. Lopez-Miranda is paid by AMGEN, SANOFI, FERRER, Esteve, and Boehringer Ingelheim-Lilly]

********CRITIQUES, RULES, AND NOTES********

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- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#heartdiseaseprevention

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:20 - Study Background
1:24 - Reversing Atherosclerosis
2:05 - Why the Mediterranean Diet?
3:30 - Heart Attack Risk?
4:06 - How does this happen?
4:43 - Main Point

References
[Study 424] Jimenez-Torres J, Alcalá-Diaz JF, Torres-Peña JD, et al. Mediterranean Diet Reduces Atherosclerosis Progression in Coronary Heart Disease: An Analysis of the CORDIOPREV Randomized Controlled Trial [published correction appears in Stroke. 2021 Nov;52(11):e754. doi: 10.1161/STR.0000000000000393.]. Stroke. 2021;52(11):3440-3449. doi:10.1161/STROKEAHA.120.033214

Funding/Conflicts: Public [Fundación Patrimonio Comunal Olivarero; Consejería de Economía, Innovación, Ciencia y Empleo; Ministerio de Ciencia e Innovación; Spanish Society of Atherosclerosis; Instituto de Salud Carlos III (ISCIII) of Spain; Directorate General for Assessment and Promotion of Research and the EU’s European Regional Development Fund (FEDER); Servicio Andaluz de Salud, Junta de Andalucia, Spain] // Potential Conflicts of Interest [Dr. Alcalá-Diaz is paid by Bayer, Grunenthal Pharma, Esteve, Ferrer, and Boehringer Ingelheim; Dr. Lopez-Miranda is paid by AMGEN, SANOFI, FERRER, Esteve, and Boehringer Ingelheim-Lilly]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#heartdiseaseprevention

Mindsip insights from this episode:

Choose Mediterranean diet to reduce heart attack risk

The Mediterranean diet significantly outperformed the low-fat diet in reducing major cardiovascular events like heart attacks and strokes over the seven-year trial.

Implement low-fat diet to halt plaque progression

While the low-fat diet did not show plaque reversal, it did appear to halt its progression, effectively stopping it from worsening.

Recognize significance of secondary prevention in coronary heart disease patients

The study was a secondary prevention trial, meaning all participants already had diagnosed coronary heart disease, making the results particularly significant.

Reverse atherosclerosis with the Mediterranean diet

In a seven-year study called the Cardioprev study, the Mediterranean diet demonstrated the ability to reverse atherosclerosis by reducing plaque in the arteries of high-risk patients.

Challenge olive oil's role in heart disease debate

In complete opposition to the study's findings, some prominent physicians and scientists claim that olive oil and the Mediterranean diet actually cause heart disease.

Enhance HDL levels to clean arteries through diet

The diet is speculated to work by increasing HDL particles that remove cholesterol from plaque through a process called reverse cholesterol transport.

Prioritize Mediterranean diet over calorie deficit for arterial health

Despite being in a greater caloric deficit, the low-fat diet group underperformed compared to the Mediterranean diet group in reducing arterial plaque.

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