The Science Of Your Gut Microbiome: How Healing Your Gut Can Improve Your Physical and Mental Health with Dr. Steven Gundry

Mark Hyman

Jan 10, 2024

Episode description

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Dr. Steven Gundry is one of the world’s top cardiothoracic surgeons and a pioneer in nutrition. He hosts a top-rated health show, The Dr. Gundry Podcast, is the founder and Director of The International Heart and Lung Institute Center for Restorative Medicine, and is the founder of Gundry MD, a line of wellness products and supplements. He is the author of New York Times bestsellers The Plant Paradox, The Plant Paradox Cookbook, The Plant Paradox Quick & Easy, and The Longevity Paradox, along with national bestsellers The Plant Paradox Family Cookbook, The Energy Paradox, Dr. Gundry’s Diet Evolution, and Unlocking the Keto Code, and has had more than three hundred articles published in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmune disease, and multiple other diseases. He just released his latest book, Gut Check: Unleash the Power of Your Microbiome to Reverse Disease and Transform Your Mental, Physical, and Emotional Health.

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In this episode we discuss (audio version / Apple Subscriber version):

How Dr. Gundry and I discovered the significance of the gut microbiome (8:05 / 5:29)
Hallmarks of a healthy microbiome (15:21 / 12:45)
Feeding the microbiome (17:11 / 14:35)
Maintaining a healthy, impenetrable gut wall through mitochondrial uncoupling (23:03 / 20:27)
The role of polyphenols in the gut microbiome (32:50 / 27:55)
Research on the microbiomes of centenarians and their ability to pr

Mindsip insights from this episode:

Identify abnormal bacteria to understand depression's microbiome link

Recent studies show that depressed individuals have a distinct 'depressive microbiome,' and you can identify these specific abnormal bacterial species.

#depression

#microbiome

Avoid oats to safeguard serotonin production

Oats, even organic ones, are often contaminated with glyphosate, an antibiotic that specifically targets and kills the gut bacteria responsible for producing serotonin.

#microbiome

#nutrition

Leverage dead bacteria in fermented foods for probiotic benefits

The cell walls of dead bacteria in fermented foods carry important messages that other bacteria read, making them as beneficial as live probiotics.

#bacteria

#probiotics

Leverage super-agers' microbiomes to neutralize environmental toxins

The microbiomes of people who live to be over 95 have a unique ability to eat and neutralize environmental toxins like plastics and petrochemicals.

#microbiome

#toxins

Optimize gut health to enhance immunotherapy effectiveness

The effectiveness of powerful immunotherapy cancer drugs can depend on having specific gut bacteria like Akkermansia, as the drugs may not work without them.

#cancer

#microbiome

Leverage Urolithin A to boost muscle strength and endurance

The postbiotic Urolithin A, made by gut bacteria from pomegranates and walnuts, has been shown in studies to increase muscle strength and endurance without any changes in exercise.

#muscle

#urolithin

Recognize gut gases as communication signals for mitochondria

Gases produced by gut bacteria, like hydrogen gas, act as 'gasotransmitters' or text messages that communicate with and regulate your mitochondria.

#hydrogen

#mitochondria

Implement mitochondrial uncoupling to enhance longevity

Intentionally 'wasting' 30% of calories via mitochondrial uncoupling protects mitochondria from damage and is a hallmark of people who live the longest.

#longevity

#mitochondria

Understand polyphenols as signaling compounds, not antioxidants

Polyphenols are not antioxidants but are actually signaling compounds that gut bacteria eat and then activate into absorbable, bioactive compounds that benefit us.