The Surprising Truth About Methylene Blue and Anti-Aging
Brad Stanfield
Feb 23, 2025
Episode description
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Here are the links to the research papers referenced in the video:
https://alphahormones.com/methylene-blue-mitochondrial-health/methylene-blue-mitochondrial-health/
https://faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.07-9610com
https://www.sciencedirect.com/science/article/abs/pii/S0197018606002531
https://pmc.ncbi.nlm.nih.gov/articles/PMC3954939/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5032683/
https://www.mayoclinicproceedings.org/article/S0025-6196(20)30985-X/fulltext
https://pmc.ncbi.nlm.nih.gov/articles/PMC5084971/
https://pubmed.ncbi.nlm.nih.gov/25018057/
https://pmc.ncbi.nlm.nih.gov/articles/PMC10631450/
https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-serious-cns-reactions-possible-when-methylene-blue-given-patients
https://www.mayoclinic.org/drugs-supplements/methylene-blue-intravenous-route/description/drg-20064695
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003889
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.121.058162
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12767
Thumbnail by James Kelly
Video edited by Troy Young
Script by John Milliken
The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.
Mindsip insights from this episode:
Boost cellular energy and protect against oxidative damage with methylene blue
Methylene blue appears to work by affecting the mitochondria, increasing cellular energy production and protecting cells from oxidative damage.
Reject methylene blue as effective anti-aging treatment based on mouse study
In a formal test, methylene blue did not statistically increase the overall lifespan of mice, leading researchers to conclude it wasn't an effective anti-aging treatment in that study.
Boost memory with low-dose methylene blue
In a human study, participants who took a single low dose of methylene blue showed increased brain activity in memory-related regions and performed better on memory tests.
Avoid methylene blue with serotonin-affecting medications to prevent serotonin syndrome
Methylene blue can cause a life-threatening condition called serotonin syndrome when taken with other medications that affect serotonin, like many common antidepressants.
Ensure supplement safety by sourcing from regulated providers
Supplements like methylene blue sourced from the internet may not be regulated and could contain unwanted contaminants such as heavy metals.
Incorporate legumes to boost life expectancy by two years
According to one study, simply adding more legumes like beans to your diet could be responsible for a gain of up to two and a half years of life expectancy.
Boost brain function with multivitamins and minerals
The large COSMOS study found that a well-designed multivitamin and mineral supplement boosted cognition, memory, and executive function in humans.
