This Gene controls Ergothioneine linked Mitochondrial Benefits
Physionic
Jul 3, 2024
Mindsip insights from this episode:
Utilize PGC1-alpha to enhance ergothioneine transporter production
The PGC1-alpha protein likely works by binding to other proteins, called transcription factors, allowing them to read the gene that creates the ergothioneine transporter.
Inhibit protein blockers to enhance ergothioneine transporter production
An alternative theory is that PGC1-alpha may stop proteins that normally inhibit the production of the ergothioneine transporter, thereby allowing it to be created.
Question real-world impact of regulatory gene increase on ergothioneine levels
A critical look at the data shows a massive 18-times increase in a regulatory gene led to only a 30% increase in ergothioneine, questioning the practical impact for humans.
Boost ergothioneine transport with exercise
New research shows that exercise first raises PGC1-alpha levels, which then increases the gene expression for the transporter that allows ergothioneine into your cells.
Leverage PGC1-alpha to regulate mitochondrial generation
The protein PGC1-alpha is described as a master regulator that controls the generation of new mitochondria.
Enhance mitochondrial function through exercise and ergothioneine
Both exercise and the molecule ergothioneine can improve mitochondrial function by stimulating the same enzyme, called npsst.
More from
Physionic
You also might be interested in
Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah
Peter’s takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6
Boost Brain Power by 25% WITHOUT a Pill (Brain Optimization Secrets)
The Biohacking Tool That Will Change the World (Mitochondrial Transfusions)
Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway)
