
Why Being Normal Weight Might Be a Death Sentence...
Physionic
Jul 24, 2025
Episode description
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0:00 - Introduction
1:53 - Relative Fat Mass
2:50 - T-O-F-I
4:18 - How can a person be overweight and healthier than you?
6:35 - Fat Depots & What to Do
9:35 - Main Points
References
[Study 491] Woolcott, O. O., Samarasundera, E., & Heath, A. K. Association of relative fat mass (RFM) index with diabetes-related mortality and heart disease mortality. Scientific Reports, 2024.
Funding/Conflicts: Public [The Third Division Tumxuk City Science and Technology Innovation Talent Program (Grant KY2025RC03); China Postdoctoral Science Foundation (Grant 2024M761177)] / No direct Conflicts of Interest
[Study 492] Agrawal S, Klarqvist MDR, Diamant N, et al. BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases. Nat Commun. 2023;14:35704. doi:10.1038/s41467-022-35704-5
Funding/Conflicts: Public [National Heart, Lung, and Blood Institute (NHLBI, NIH); National Institute on Aging (NIA, NIH)] // No direct Conflicts of Interest
[Study 493] Karpe, F., & Pinnick, K. E. (2014). Biology of upper-body and lower-body adipose tissue—link to whole-body phenotypes. Nature Reviews Endocrinology. Advance online publication.
Funding/Conflicts: Public [National Institute on Aging (NIA, NIH)] // No direct Conflicts of Interest
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