Anti-Aging through eating Garlic: New Molecule Discovered!

Physionic

Jun 11, 2026

Episode description

JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

HEALTH AUTONOMY [COURSE]
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

JOIN THE COMMUNITY
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

EMAIL LIST
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

HIRE ME FOR CONSULTING:
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:34 - S1PC, eNAMPT, and more Incoherent Letters and Numbers
5:25 - We are Human, Afterall
6:36 - Early Research for Exciting Beginnings

References
[Study 808] Suzuki JI, Yoshioka K, Kurita M, et al. Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signaling. Cell Metab. 2026;38:1-11.e10. doi:10.1016/j.cmet.2026.04.006.

Funding/Conflicts: Public Funding: From the study, no public funding source was reported; Non-Profit Funding: From the study, no non-profit funding source was reported; Industry Funding: From the study, no industry funding source was reported, and no conflict-of-interest statement was found in the accessible full-text record. The author affiliations included Maastricht University/NUTRIM and the Top Institute Food and Nutrition, but these were listed as affiliations rather than explicit funding sources.

[Study 809] Ried K, Paye Y, Beale D, Sali A. Kyolic aged garlic extract improves aerobic fitness in middle-aged recreational endurance athletes: a randomized double-blind placebo-controlled 3 month trial. Exp Ther Med. 2025;29:86. doi:10.3892/etm.2025.12836.

Funding/Conflicts: Public Funding: From the study, no public funding source was reported; Non-Profit Funding: From the study, no non-profit funding source was reported; Industry Funding: From the study, KR received travel sponsorship from Wakunaga of America Co., Ltd., and the trial was supported by a Wakunaga of America Co., Ltd. grant that supplied trial capsules and funded testing costs, research assistance, and open-access publication, while the sponsor was not involved in study design, data collection, analysis, or manuscript preparation;
the authors declared no competing interests.

[Study 810] Punduk Z. Aged garlic supplementation improves muscle performance properties in untrained male. Electron J Biol. 2016;12(3):222-228.

Funding/Conflicts: Public Funding: From the study, the work was supported by the Balikesir University Scientific Research Project, grant no. 2014/68, Turkey, and no other organization or institution cofinanced the research; Non-Profit Funding: From the study, no non-profit funding source was reported; Industry Funding: From the study, no industry funding source was reported, AGE supplementation was provided by Prof. Dr. Khalid Rahman from Liverpool John Moores University, and the author declared no competing interests.

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Mindsip insights from this episode:

Maximize S1PC benefits in older adults for enhanced brain signaling

The benefits of S1PC might be significantly greater in older people, as the mild effects seen so far were in younger adults whose brain signaling is still optimal.

Utilize garlic molecule S1PC to enhance NAD pathway

The garlic molecule S1PC unexpectedly works through the popular NAD pathway, which is critical for cellular energy and repair.

Enhance fat-brain-muscle communication with S1PC enzyme release

S1PC prompts fat tissue to release an enzyme that boosts NAD in the brain's hypothalamus, which in turn improves communication with the muscles.

Avoid S1PC supplements until safety is established

There are currently no S1PC-specific supplements available, as the safety of such concentrated amounts has not been established.

Discover S1PC in aged garlic for anti-aging benefits

A molecule in aged garlic called S1PC (S1-propenyl-L-cysteine), not the well-known allicin, has shown anti-aging promise in new research.

Leverage aged garlic extract for improved muscle power

Human studies on aged garlic extract, which naturally contains S1PC, indicate mild improvements in muscle power.

Supplement S1PC to boost eNAMPT and NAD levels

In humans, supplementing with S1PC has been shown to raise blood levels of eNAMPT, a key enzyme for producing NAD.

Enhance muscle performance with S1PC signaling

In animal studies, S1PC improved muscle force generation by enhancing the brain's ability to signal muscles to contract.

DOWNLOAD THE APP

Unlock the wisdom of longevity

DOWNLOAD THE APP

Unlock the wisdom of longevity

Unlock the wisdom of longevity

© Mindsip 2025 – Made with ❤ in Vilnius

Unlock the wisdom of longevity

© Mindsip 2025 – Made with ❤ in Vilnius