
Arterial Plaque Traps Inflammation - Fish Oil may Release it
Physionic
Sep 6, 2025
Mindsip insights from this episode:
Guide immune cells from plaque using CCR7 protein
A protein called CCR7 can guide immune cells out of the plaque and into the lymphatic system, much like a plane being guided by runway lights.
Utilize DHA to reduce immune cell adhesion in inflammation
In a pro-inflammatory environment, the omega-3 fat DHA shows a strong dose-response reduction in the adhesion proteins that allow immune cells to invade plaque.
Reduce artery stickiness with omega-3 fats
Omega-3 fats reduce 'adhesion molecules' on artery walls, making it harder for immune cells to grab on and invade the plaque.
Address unstable arterial plaque to combat inflammation
Dangerous arterial plaque is often unstable because it's bloated with immune cells that have become pro-inflammatory in a failed attempt to clear out cholesterol.
Stabilize arterial plaque to reduce rupture risk
We want to stabilize plaque in our arteries because stable plaque is less likely to rupture and cause damage compared to soft, unstable plaque.
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