Cleveland Clinic says Erythritol causes Dangerous Clotting - Why?
Physionic
Dec 30, 2024
Episode description
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2
*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy
*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2
*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6
*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H
Created with Biorender
0:00 - Introduction
0:24 - Why is the Cleveland Clinic blaming Erythritol?
0:56 - How Erythritol is involved in Clotting
2:25 - Study Design
2:42 - Erythritol on Clotting Data
5:10 - Critiques of the Study
7:55 - Main Points
References
[Study 381] Witkowski M, Wilcox J, Province V, et al. Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report. Arterioscler Thromb Vasc Biol. 2024;44(9):2136-2141. doi:10.1161/ATVBAHA.124.321019
Funding/Conflicts: Public Funding [National Institute of Health, Deutsche Forschungsgemeinschaft] / Potential Conflicts of Interest [Some researchers hold cardiovascular diagnostics patents / Consulting for Pharma]
[A] Cleveland Clinic. Cleveland Clinic study adds to increasing evidence that sugar substitute erythritol raises cardiovascular risk. News release. August 8, 2024. Accessed December 29, 2024. https://newsroom.clevelandclinic.org/2024/08/08/cleveland-clinic-study-adds-to-increasing-evidence-that-sugar-substitute-erythritol-raises-cardiovascular-risk
[B] Witkowski M, Nemet I, Alamri H, et al. The artificial sweetener erythritol and cardiovascular event risk. Nat Med. 2023;29(3):710-718. doi:10.1038/s41591-023-02223-9
********CRITIQUES, RULES, AND NOTES********
Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).
Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:
Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.
RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.
If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).
Please use the following link to submit your critique: https://bit.ly/PhysionicCritique
Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
#erythritol #heartdiseaseprevention #heartdiseasetreatment
Mindsip insights from this episode:
Limit erythritol intake to reduce platelet aggregation risk
In a human study, consuming 30 grams of erythritol statistically increased platelet aggregation (clotting) 30 minutes later when compared to baseline.
Investigate transient effects on blood platelets post-consumption
The negative effects on blood platelets were only measured 30 minutes after consumption, and it's unknown if these effects persist hours later.
Reevaluate long-term studies linking erythritol to heart attacks
Previous long-term studies linking blood erythritol to heart attacks are flawed because participants with higher levels also tended to be sicker to begin with.
Consume erythritol in moderation without concern
If you consume erythritol in passing or in small amounts, like in gum, there is likely no need to change your habits based on current evidence.
Compare erythritol doses in processed foods and natural sources
The study used a 30-gram dose, common in processed foods, whereas erythritol found naturally in fruits is often less than 100 milligrams.
Investigate erythritol's effect on blood platelet activation
The sugar substitute erythritol is believed to activate blood platelets, potentially through calcium signaling, which can lead them to clump together.
