Ergothioneine: New Supplement discovered to Improve Mitochondrial Function [Study 295]
Physionic
May 27, 2024
Mindsip insights from this episode:
Boost ergothioneine levels in muscle mitochondria through exercise
A new, unpublished study shows that exercise increases concentrations of the amino acid ergothioneine within muscle mitochondria.
Boost ergothioneine function through exercise
Exercise not only increases ergothioneine levels but also increases the expression of the MPST enzyme that ergothioneine requires to function.
Boost ergothioneine levels through endurance and resistance training
Data from previous human studies confirms that both endurance and resistance training increase the levels of ergothioneine found in the blood.
Boost physical performance by supplementing ergothioneine
In a mouse study, supplementing the diet with ergothioneine improved physical performance by almost 30% without any additional exercise.
Ensure MPST enzyme for ergothioneine's mitochondrial benefits
The mitochondrial benefits of ergothioneine are dependent on an enzyme called MPST, as inhibiting this enzyme negates ergothioneine's positive effects.
Boost mitochondrial function with ergothioneine supplementation
When added directly to muscle cells in a lab, ergothioneine was shown to increase oxygen consumption, which is a direct proxy for improved mitochondrial function.
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