Exclusive Dr. Hyman+ Ask a Doctor: Gut Health and Alzheimer’s, Genetic Risk of Disease, And More

Mark Hyman

Jan 30, 2024

Episode description

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.

In this teaser episode, you’ll hear a preview of our monthly Ask A Doctor Anything episode with Dr. Elizabeth Boham.

Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of:

- Ad-Free Doctor’s Farmacy Podcast episodes

- Exclusive monthly Functional Medicine Deep Dives

- Monthly Ask Mark Anything Episodes

- Bonus audio content exclusive to Dr. Hyman+

Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at plus@drhyman.com with any questions you have.

Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

Episode description

In this teaser episode, you’ll hear a preview of our monthly Ask A Doctor Anything episode with Dr. Elizabeth Boham.

Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of:

- Ad-Free Doctor’s Farmacy Podcast episodes

- Exclusive monthly Functional Medicine Deep Dives

- Monthly Ask Mark Anything Episodes

- Bonus audio content exclusive to Dr. Hyman+

Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at plus@drhyman.com with any questions you have.

Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

Mindsip insights from this episode:

Understand APOE4 gene as risk factor, not a certainty for dementia

The APOE4 gene is considered a 'low penetrance' gene, meaning it increases dementia risk but does not guarantee you will get the disease.

#APOE4

#dementia

Manage hormones to influence Lipoprotein(a) levels

Hormonal shifts like menopause or hypothyroidism can elevate Lipoprotein(a), and hormone replacement therapy can sometimes lower it by 20-30%.

#hormones

#menopause

Lower Lp(a) levels with PCSK9 inhibitors

A newer class of cholesterol medications called PCSK9 inhibitors can lower Lipoprotein(a) levels by 20-30%.

#cholesterol

Beware statins: they may increase Lipoprotein(a) levels

Statin medications like Lipitor and Crestor do not lower Lipoprotein(a) and may, in fact, slightly increase it.

#cholesterol

#statin

Get tested for lipoprotein(a) to establish baseline risk

Because Lipoprotein(a) levels are largely genetic and stable, it is often considered a once-in-a-lifetime test to establish your baseline risk.

#genetics

#testing

Aim for higher omega-3 index of 8-12% if APOE4 positive

For individuals with the APOE4 gene, the target for the Omega-3 Index should be higher than average, aiming for 8-12% instead of the standard 8%.

#APOE4

#omega-3

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