How the Gut Microbiome Influences Everything from Cancer Treatment to Inflammation

Mark Hyman

Feb 19, 2024

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Your gut microbiome is your inner garden—the more good bugs you have in it, the more likely it is to flourish. Our gut bacteria regulate many bodily functions, from creating vitamins to controlling our immune system, brain function, and, of course, our metabolism and weight. They are critical to our long-term health. But even if you’re eating the right things, you may need outside assistance to maintain plentiful and diverse gut bacteria.



In today’s episode, I talk with Dr. Steven Gundry, Dr. Mark Pimentel, Dr. Uma Naidoo, and Dr. Zach Bush about the importance of the microbiome and why it should be considered in any disease treatment plan.



This episode is brought to you by Rupa Health, Cozy Earth, AG1, and Essentia.



Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.



Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com and use code DRHYMAN.



Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get 10 FREE travel packs and a FREE Welcome Kit with your first order.



Receive an extra $100 off your mattress purchase! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.





Episode description

View the Show Notes For This Episode



Get Free Weekly Health Tips from Dr. Hyman



Sign Up for Dr. Hyman’s Weekly Longevity Journal



Get Ad-free Episodes & Dr. Hyman+ Audio Exclusives



Your gut microbiome is your inner garden—the more good bugs you have in it, the more likely it is to flourish. Our gut bacteria regulate many bodily functions, from creating vitamins to controlling our immune system, brain function, and, of course, our metabolism and weight. They are critical to our long-term health. But even if you’re eating the right things, you may need outside assistance to maintain plentiful and diverse gut bacteria.



In today’s episode, I talk with Dr. Steven Gundry, Dr. Mark Pimentel, Dr. Uma Naidoo, and Dr. Zach Bush about the importance of the microbiome and why it should be considered in any disease treatment plan.



This episode is brought to you by Rupa Health, Cozy Earth, AG1, and Essentia.



Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.



Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com and use code DRHYMAN.



Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get 10 FREE travel packs and a FREE Welcome Kit with your first order.



Receive an extra $100 off your mattress purchase! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.





Mindsip insights from this episode:

Boost fitness with Urolithin A from pomegranates

The postbiotic Urolithin A, which only some people's gut bacteria can produce from foods like pomegranates, has been shown in studies to increase muscle endurance and fitness levels even without exercise.

Leverage postbiotics from dead bacteria for gut health benefits

The cell walls of dead bacteria in fermented foods like yogurt contain important messages (postbiotics) that living bacteria read to perform their functions, making them just as beneficial as live cultures.

Beware glyphosate's impact on mood-regulating gut bacteria

The weed killer glyphosate was patented as an antibiotic and specifically destroys gut bacteria responsible for producing the mood-regulating neurotransmitters serotonin and GABA.

Leverage unique microbiome of supercentenarians to combat environmental toxins

People who live healthily past 95 years old have a unique microbiome capable of metabolizing and breaking down xenobiotics, which are harmful environmental toxins like plastics and chemicals.

Recognize IBS as an autoimmune-like gut disease

Irritable Bowel Syndrome (IBS) can be an autoimmune-like disease of the gut's nerves, triggered by antibodies that the body creates in response to food poisoning.

Treat hydrogen sulfide SIBO with Rifaximin and Pepto-Bismol

The hydrogen sulfide form of SIBO (Small Intestinal Bacterial Overgrowth) can be treated with a combination of the antibiotic Rifaximin and bismuth, the active ingredient in the over-the-counter product Pepto-Bismol.

Utilize ancient soil molecules to repair leaky gut

Molecules extracted from 60-million-year-old fossilized soil can provide a stable communication network for cells, allowing them to repair the gut lining and reverse leaky gut caused by chemicals like glyphosate.

Protect gut health to safeguard brain function

The blood-brain barrier is not directly harmed by gluten and Roundup, but it "blows apart" after the gut lining is first exposed to these compounds, showing the gut is the first line of defense.

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