
India's Air Pollution + Hyperbaric Oxygen Therapy | Bryan Johnson Podcast #4
Bryan Johnson
May 2, 2025
Mindsip insights from this episode:
Choose hard-shell HBOT chamber for optimal longevity benefits
For longevity, you need a hard-shell chamber that reaches at least 2.0 atmospheres (ATA) and delivers 100% oxygen via a mask to avoid causing cataracts.
Take NAC or glutathione to combat air pollution effects
If you are exposed to poor air quality, taking supplements like N-acetylcysteine (NAC) or glutathione can help manage the resulting inflammation and oxidative stress.
Avoid outdoor exercise when PM2.5 exceeds 70; wear N95 above 150
As a general rule, you should avoid exercising outside if the PM2.5 air quality is above 70 and wear an N95 mask if it's above 150.
Challenge cultural norms of 'eating death' to promote health
Just as India has become normalized to 'breathing death' from air pollution, America has become normalized to 'eating death' from widespread obesity.
Address air pollution to enhance lifespan more than cancer solutions
In India, solving the air pollution problem would extend the population's lifespan more than solving all forms of cancer.
Verify your oxygen source for optimal delivery
It's important to verify your oxygen source, as a common oxygen concentrator was found to only deliver 89-92% oxygen, prompting a switch to medical-grade cylinders for 100%.
Utilize HBOT as a hormetic stressor to enhance regeneration
The therapy works as a hormetic stressor by using high oxygen levels to cause temporary oxidative damage, which upregulates the body's long-lasting regenerative systems.
Utilize HBOT to eliminate systemic inflammation
Following a 60-session protocol, the hs-CRP test for systemic inflammation could not even detect levels of inflammation in the body.
Utilize hyperbaric oxygen therapy for superior skin remodeling
Hyperbaric oxygen therapy is considered the most effective skin remodeling therapy in the world, surpassing lasers and fillers for a whole-body skin glow.
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