Taurine’s Multiple Blood Pressure Lowering Effects

Physionic

Dec 9, 2024

Episode description

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0:00 - Introduction
0:18 - Why Taurine matters
1:12 - Reducing the Effect of Angiotensin 2
5:43 - Taurine modulates Epinephrine
7"50 - Take Aways

References
[Study 193] Singh P, Gollapalli K, Mangiola S, et al. Taurine deficiency as a driver of aging. Science. 2023;380(6649):eabn9257. doi:10.1126/science.abn9257

Public Funding - NIH and affiliates. Conflict of Interest: One of the researchers has a patent with Columbia University

[Study 347] Tzang CC, Chi LY, Lin LH, et al. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. Nutr Diabetes. 2024;14(1):29. Published 2024 May 16. doi:10.1038/s41387-024-00289-z

Public Funding: National Taiwan University Hospital and the Ministry of Science and Technology // No Conflicts of Interest

[Study 364] Bkaily G, Jazzar A, Normand A, Simon Y, Al-Khoury J, Jacques D. Taurine and cardiac disease: state of the art and perspectives. Can J Physiol Pharmacol. 2020;98(2):67-73. doi:10.1139/cjpp-2019-0313

Funding/Conflicts: Unknown

[Study 365] Wójcik OP, Koenig KL, Zeleniuch-Jacquotte A, Costa M, Chen Y. The potential protective effects of taurine on coronary heart disease. Atherosclerosis. 2010;208(1):19-25. doi:10.1016/j.atherosclerosis.2009.06.002

Funding/Conflicts: Public Funding [National Institute of Health / American Heart Association] / Unknown Conflicts

[A] Lin YJ, Kwok CF, Juan CC, et al. Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor. Biochem Biophys Res Commun. 2014;451(2):263-269. doi:10.1016/j.bbrc.2014.07.119

[B] Fujita T, Ando K, Noda H, Ito Y, Sato Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation. 1987;75(3):525-532. doi:10.1161/01.cir.75.3.525

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#taurine #hearthealthtips #hearthealthawareness

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:18 - Why Taurine matters
1:12 - Reducing the Effect of Angiotensin 2
5:43 - Taurine modulates Epinephrine
7"50 - Take Aways

References
[Study 193] Singh P, Gollapalli K, Mangiola S, et al. Taurine deficiency as a driver of aging. Science. 2023;380(6649):eabn9257. doi:10.1126/science.abn9257

Public Funding - NIH and affiliates. Conflict of Interest: One of the researchers has a patent with Columbia University

[Study 347] Tzang CC, Chi LY, Lin LH, et al. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. Nutr Diabetes. 2024;14(1):29. Published 2024 May 16. doi:10.1038/s41387-024-00289-z

Public Funding: National Taiwan University Hospital and the Ministry of Science and Technology // No Conflicts of Interest

[Study 364] Bkaily G, Jazzar A, Normand A, Simon Y, Al-Khoury J, Jacques D. Taurine and cardiac disease: state of the art and perspectives. Can J Physiol Pharmacol. 2020;98(2):67-73. doi:10.1139/cjpp-2019-0313

Funding/Conflicts: Unknown

[Study 365] Wójcik OP, Koenig KL, Zeleniuch-Jacquotte A, Costa M, Chen Y. The potential protective effects of taurine on coronary heart disease. Atherosclerosis. 2010;208(1):19-25. doi:10.1016/j.atherosclerosis.2009.06.002

Funding/Conflicts: Public Funding [National Institute of Health / American Heart Association] / Unknown Conflicts

[A] Lin YJ, Kwok CF, Juan CC, et al. Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor. Biochem Biophys Res Commun. 2014;451(2):263-269. doi:10.1016/j.bbrc.2014.07.119

[B] Fujita T, Ando K, Noda H, Ito Y, Sato Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation. 1987;75(3):525-532. doi:10.1161/01.cir.75.3.525

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#taurine #hearthealthtips #hearthealthawareness

Mindsip insights from this episode:

Supplement taurine to lower epinephrine in high blood pressure

In humans with high blood pressure, taurine supplementation has been shown to significantly reduce levels of the hormone epinephrine.

Balance taurine exposure to manage calcium levels

While short-term taurine exposure can temporarily increase cell-contracting calcium, long-term exposure leads to a marked drop in calcium, relaxing blood vessels.

Utilize taurine to lower blood pressure by opposing angiotensin II

Taurine helps lower blood pressure by acting as an antagonist to the hormone angiotensin II, which normally constricts blood vessels.

Maintain taurine levels to combat aging effects

According to an influential paper in 'Science', blood taurine levels can drop to less than half of youthful levels as we age.

Recognize taurine's modest impact on blood pressure reduction

While the blood pressure-lowering effect of taurine appears to be consistent across studies, the overall effect isn't huge.

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