The Science of Weight Loss: What You Need to Know

Mark Hyman

Jun 7, 2024

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Why is it so hard to lose weight and keep it off? On this episode of "The Doctor's Farmacy," we explore the intricate science of weight gain and metabolism, debunking common myths about calorie counting and your diet. Emphasizing the importance of food quality over quantity, I'll examine how modern diets high in refined carbs and sugars contribute to obesity. By investigating root causes and offering a holistic approach, I’ll provide you with a science-backed roadmap to achieving sustainable weight loss and optimal metabolic health.

This episode is brought to you by AG1 and Fatty 15.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order.

Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 10% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

Episode description

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

Sign Up for Dr. Hyman’s Weekly Longevity Journal

Why is it so hard to lose weight and keep it off? On this episode of "The Doctor's Farmacy," we explore the intricate science of weight gain and metabolism, debunking common myths about calorie counting and your diet. Emphasizing the importance of food quality over quantity, I'll examine how modern diets high in refined carbs and sugars contribute to obesity. By investigating root causes and offering a holistic approach, I’ll provide you with a science-backed roadmap to achieving sustainable weight loss and optimal metabolic health.

This episode is brought to you by AG1 and Fatty 15.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order.

Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 10% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

Mindsip insights from this episode:

Investigate calorie paradox: declining intake vs rising obesity rates

According to government data (NHANES), Americans' calorie and added sugar intake has gone down since 2000, yet obesity and type 2 diabetes rates have continued to rise.

Discover pentadecanoic acid for superior cellular benefits

A newly discovered essential fat, pentadecanoic acid (C15), has been shown in research to have three times the cellular benefits of omega-3 fatty acids.

Understand obesity as starvation amidst plenty

High insulin levels lock fuel in your fat cells, so your brain perceives a low-energy state, making you feel hungry and crave sugar even when you have abundant stored energy.

Reevaluate nut calorie counts based on absorption rates

The body extracts 32% fewer calories from almonds and 21% fewer from walnuts than what is stated on the nutrition label due to the food's complex structure.

Choose macadamia nuts for low-carb and optimal omega ratio

Macadamia nuts have the lowest carbohydrate content among nuts, with 50% less than cashews, and boast one of the best omega 6-to-3 ratios.

Overcome weight-loss plateau by addressing toxin release

When you lose weight, stored toxins are released from fat tissue, which can poison your mitochondria and thyroid, slowing your metabolism and causing a plateau.

Combat obesogens to prevent weight gain

Environmental chemicals called 'obesogens' can cause weight gain by disrupting thyroid function, promoting insulin resistance, and altering your stress response.

Surround yourself with healthy friends to combat weight gain

You are 171% more likely to be overweight if your friends are overweight, which is a far stronger influence than having overweight parents or siblings.

Recognize sugar's addictive effects on the brain

A study showed high-glycemic milkshakes activate the brain's addiction center (nucleus accumbens) in the same way as opioids, even with identical calories and macros as low-glycemic shakes.

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