This Incredibly Popular Supplement DAMAGES Your Blood Vessels
Brad Stanfield
Apr 30, 2025
Mindsip insights from this episode:
Obtain calcium from food to reduce artery calcification risk
Getting calcium from food is the safest approach, as high dietary intake is linked to a 27% lower risk of artery calcification.
Limit iron supplements to protect zinc levels and organs
Taking too much iron from supplements can reduce zinc levels and cause organ damage, so it's best to get it from your diet unless prescribed by a doctor.
Reconsider vitamin E supplementation to avoid increased mortality
A Cochrane analysis of almost 300,000 people suggests that supplementing with vitamin E, a popular antioxidant, might actually increase mortality.
Avoid high doses of vitamin A supplements to protect health
Similar to vitamin E, high doses of vitamin A supplements are also associated with increased mortality and can weaken bones and damage the liver.
Reevaluate resveratrol claims after lab error revelation
The initial excitement for resveratrol was based on a study claiming it extended yeast lifespan by 70%, which was later revealed to be a lab error.
Avoid resveratrol to maximize exercise benefits
Resveratrol supplementation was found to reduce the positive effects of high-intensity exercise on blood pressure, cholesterol, and oxygen utilization.
Avoid calcium supplements to reduce heart attack risk
Taking calcium supplements is linked to a 30-90% increased risk of heart attacks because they spike blood calcium levels, unlike dietary calcium.
Reevaluate resveratrol's role in activating SIRT1 for longevity
Recent research using CRISPR technology found that resveratrol does not directly activate the longevity enzyme SIRT1, but instead stresses cells by interfering with DNA copying.
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