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Physionic

Oct 7, 2024

Episode description

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Reference
[Study 345] Neal B, Wu Y, Feng X, et al. Effect of Salt Substitution on Cardiovascular Events and Death. N Engl J Med. 2021;385(12):1067-1077. doi:10.1056/NEJMoa2105675

Public Funding - National Health and Medical Research Council of Australia

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2
Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro

*Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More

*Pro Tier:* All benefits of the Standard Tier + Live Sessions with Me, Consulting Lite, and More

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
One Weekly Email of Value: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

*DONATIONS FOR A SCIENCE BASED CAUSE*
Patreon: https://bit.ly/PhysionicPatreon

*OTHER SOCIAL MEDIA*
Instagram: http://bit.ly/2OBFe7i

Reference
[Study 345] Neal B, Wu Y, Feng X, et al. Effect of Salt Substitution on Cardiovascular Events and Death. N Engl J Med. 2021;385(12):1067-1077. doi:10.1056/NEJMoa2105675

Public Funding - National Health and Medical Research Council of Australia

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

Mindsip insights from this episode:

Address open-label design to enhance study validity

A noted weakness of the study was its open-label design, meaning participants knew if they were using the salt substitute, which could have influenced the results.

Utilize salt substitute blend for cardiovascular protection

A blend of 75% sodium chloride and 25% potassium chloride was used to replace regular salt, leading to significant protective cardiovascular effects.

Implement small changes to lower blood pressure and reduce heart attack risk

A seemingly small drop of just over three units in systolic blood pressure can compound over five years to significantly reduce heart attacks and strokes.

Avoid potassium chloride to protect kidney health

Substituting salt with potassium chloride can be harmful for individuals with kidney issues, as the resulting sodium-potassium imbalance can cause heart problems.

Reduce major cardiovascular events with salt substitute

Over five years, using the salt substitute statistically reduced the rate of major adverse cardiovascular events (MACE), which includes heart attacks and strokes.

Recognize minimal impact of salt substitute on diastolic pressure

The salt substitute had a tiny effect on diastolic blood pressure (the lower number), reducing it by only about half a unit, which may not be statistically significant.

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