
Transform Your Metabolic Health & Longevity by Knowing Your Unique Biology | Dr. Michael Snyder
Andrew Huberman
Sep 8, 2025
Mindsip insights from this episode:
Explore GLP-1 agonists for cognitive enhancement and longevity
GLP-1 agonists like Ozempic are being explored as potential longevity drugs, partly due to evidence they may improve cognition.
Personalize fiber intake to optimize cholesterol reduction
In a study, Arabinoxylan fiber (in Metamucil) lowered cholesterol for most, but for some individuals, Inulin was more effective.
Recognize type 2 diabetes sub-phenotypes for tailored treatments
Type 2 diabetes is not a single disease but can be subdivided into different forms like muscle resistance or beta-cell defects, which require different treatments.
Exercise in the morning to improve glucose control for insulin resistance
People with muscle insulin resistance get better glucose control benefits by exercising in the morning, which is contrary to general advice.
Identify fibers that may trigger inflammation in your body
Contrary to popular belief, certain types of fiber can cause systemic inflammation in some individuals while reducing it in others.
Understand personal glycemic responses to optimize diet
The glycemic index is highly personal, with some people spiking glucose to potatoes but not grapes, and vice versa.
Recognize viral infections as triggers for diabetes risk
A viral infection can trigger latent, genetically-predisposed diabetes by causing long-term epigenetic changes to metabolic genes.
Engage in immersive events to enhance mental health and reduce inflammation
Immersive psychological events, like those from Tony Robbins, have been shown in studies to improve not just mental health surveys but also physical inflammatory markers.
Prioritize ageotypes over biological age for actionable health interventions
Instead of a single biological age, we have personal aging pathways called 'ageotypes' (e.g., metabolic, immune) which are more actionable for health interventions.
Utilize Iollo home test to discover your personal ageotype
A commercially available home test from a company called Iollo uses a few drops of blood to profile 650 metabolites and determine your personal ageotype.
More from
Andrew Huberman
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners
How to Speak Clearly & With Confidence | Matt Abrahams
Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman
How Your Thoughts Are Built & How You Can Shape Them | Dr. Jennifer Groh


















