Creatine causes Kidney Disease? Why I still take it (with worsening kidney values)

Physionic

Jan 29, 2024

Episode description

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References (Copy & Paste DOI into Search Engine)
[1] doi:10.1186/s12970-017-0173-z
[2] Kreider RB, Melton C, Rasmussen CJ, et al. Long-term creatine supplementation does not significantly affect clinical markers of health in athletes. Mol Cell Biochem. 2003;244(1-2):95-104.
[3] doi:10.1093/toxres/tfaa028
[4] https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/kidney-disease/laboratory-evaluation/glomerular-filtration-rate/estimating

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#creatine #kidneydisease #creatinesafe

Episode description

Mindsip insights from this episode:

Expect significant eGFR drop with creatine supplementation

A significant 20 or even 30-point drop in eGFR measures can be expected when supplementing with creatine and does not necessarily indicate kidney damage.

#creatine

#supplement

Rethink eGFR test reliability for creatine users

The eGFR kidney function test is an unreliable estimate for creatine users because its calculation is heavily reliant on creatinine values.

#kidney

#testing

Monitor creatinine levels when supplementing with creatine

Creatine supplementation naturally increases blood creatinine levels, which is a key marker used to assess kidney function.

#blood-test

#creatine

Rethink eGFR reliance for kidney health in muscular individuals and creatine users

The National Institute of Kidney Disease states that individuals who are muscular or consume creatine should not rely solely on eGFR to assess kidney health.

#kidney

#testing

Test urea and protein for accurate kidney health assessment on creatine

To accurately assess kidney health while taking creatine, test for other molecules filtered by the kidneys, such as urea and protein, which are not influenced by creatine consumption.