Creatine’s Multiple Brain Effects
Physionic
Feb 5, 2025
Mindsip insights from this episode:
Target creatine's specific effect on brain health
The effect of creatine on the brain is specific, as it increases the PSD95 protein without altering other structural proteins like actin.
Utilize creatine to enhance cognitive performance during critical thinking
The brain-boosting effects of creatine are particularly potent during high-energy demand situations like critical thinking, as this is when its ability to regenerate ATP is most needed.
Enhance brain cell signaling efficiency with PSD95 protein
The PSD95 protein acts like an anchor, physically attaching key communication receptors to a neuron's structure, thereby increasing the efficiency of brain cell signaling.
Enhance mitochondrial energy production with creatine supplementation
Creatine supplementation specifically improves the mitochondria's ability to generate usable energy (ATP) from its precursor ADP, but does not change their maximal respiration rate.
Leverage PSD95 protein to enhance brain learning and adaptability
A protein called PSD95 is crucial for your brain's ability to change and learn by anchoring communication receptors in your neurons.
Boost PSD95 protein with creatine for enhanced learning
Creatine supplementation was shown to increase levels of the PSD95 protein by over 50%, which is vital for stabilizing neuron connections and enhancing learning.
