Dr. David Sinclair: “Only 10 Minutes a Week Reverses Aging – Here’s the Proof”
Rangan Chatterjee
Jul 21, 2025
Mindsip insights from this episode:
Engage in 10 minutes of high-intensity exercise for longevity
Just 10 minutes of high-intensity exercise a few times a week, where you get out of breath, appears sufficient for long-term health benefits.
Boost testosterone by strengthening leg muscles
Maintaining large leg and butt muscles through exercise can signal the testes to naturally correct and raise testosterone levels.
Build muscle using plant-based protein sources
It's a fallacy that you need meat to build muscle; you can get enough protein from plant-based sources without over-activating the mTOR pathway.
Engage in endurance activities to enhance longevity
There is a very clear correlation with longevity for people who run or bike long distances.
Boost endurance with NMN for enhanced performance
The molecule NMN restored blood vessels in mice and allowed them to run 50% further without any prior training.
Reset old muscle energy production with exercise or NMN
Old muscle mistakenly thinks it lacks oxygen and shuts down energy production, a state which can be reset by shocking the system with exercise or NMN.
Leverage NMN and resveratrol for marathon success at any age
A 50-year-old marathon runner who takes NMN and resveratrol is now a world champion for his age group, often beating 30-year-olds.
Defy age: Build muscle at 80 and beyond
It's a fallacy that older people cannot build muscle, as demonstrated by an 82-year-old who built significant muscle and feels better than he did in his 30s.
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