
I Made Myself Younger (RESULTS)
Bryan Johnson
Jun 19, 2025
Mindsip insights from this episode:
Evaluate every calorie for maximum longevity benefit
His diet is based on the philosophy that every single calorie consumed must be rigorously evaluated for its maximum potential longevity benefit.
Reverse sperm health decline to achieve youthful vitality
Despite a 50% global decline in sperm health over the past 50 years, he has improved his to be on par with someone in their early 20s.
Measure your aging speed with epigenetic testing
Using epigenetic testing, he measures his speed of aging and has achieved a rate of 0.48, meaning for every calendar year that passes, he only ages about half a year.
Base protocol on scientific evidence from population studies
Contrary to popular belief, his protocol is not just an n-of-1 experiment but is based on scientific evidence from large population-level studies.
Reevaluate rapamycin's impact on aging speed
The popular anti-aging drug rapamycin was found to accelerate his speed of aging, according to his specific epigenetic measurements.
Lower resting heart rate before bed to enhance health
The most impactful thing you can do for your health is to lower your resting heart rate before bed, as this improves sleep and has a compounding positive effect on diet and exercise.
Understand organ age differences for better health insights
Different parts of the body age at different rates; for example, his heart functions like a 37-year-old's, but his left ear has the biological age of a 64-year-old.
Aim for zero systemic inflammation to achieve optimal health
A key goal is to eliminate systemic inflammation, with his high-sensitivity CRP (a key inflammatory marker) coming back as non-detectable.
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