Tools for Nutrition & Fitness | Dr. Layne Norton

Andrew Huberman

Aug 12, 2024

Episode description

In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity.

We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health.

We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others.

Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness.

Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-layne-norton-tools-for-nutrition-fitness

Pre-order Andrew's new book, Protocols: https://protocolsbook.com

*Thank you to our sponsors*
AG1: https://drinkag1.com/huberman
Mateina: https://drinkmateina.com/huberman
Eight Sleep: https://www.eightsleep.com/huberman
Maui Nui: https://mauinuivenison.com/huberman
LMNT: https://drinklmnt.com/huberman

*Huberman Lab Social & Website*
Instagram: https://www.instagram.com/hubermanlab
Threads: https://www.threads.net/@hubermanlab
Twitter: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
LinkedIn: https://www.linkedin.com/in/andrew-huberman
Website: https://www.hubermanlab.com
Newsletter: https://www.hubermanlab.com/newsletter

*Dr. Layne Norton*
Website: https://biolayne.com
REPS Research Review: https://biolayne.com/reps
Carbon Diet Coach: https://www.joincarbon.com
Books: https://biolaynestore.com/collections/accessories
X: https://x.com/BioLayne
Facebook: https://www.facebook.com/LayneNorton
Instagram: https://www.instagram.com/biolayne
TikTok: https://www.tiktok.com/@biolayne
YouTube: https://www.youtube.com/@biolayne1

*Timestamps*
00:00:00 Dr. Layne Norton
00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui
00:06:39 Science-Based Evidence, Mechanism vs. Outcome
00:14:31 Meta-analysis, Methods, Evidence Quality
00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data
00:33:53 Sponsor: AG1
00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis
00:42:01 Protein Synthesis, Refractory Response; Resistance Training
00:46:05 Protein Intake, Intermittent Fasting & Training
00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis
01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth
01:05:34 Sponsor: LMNT
01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c
01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet
01:19:50 “The Norton Method”; Tool: Consistency
01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest
01:33:50 Mind & Body Effects, Stress; Belief Effects
01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training
01:50:24 Fatigue & Training to Failure, Speed, Strength Training
01:59:06 Tool: Training After 50, Consistency
02:09:12 Fat Cells, Diabetes, Exercise
02:16:50 Metabolism & Age-Related Changes?, Appetite
02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise”
02:33:42 GLP-1 Agonists, Judgement & Obesity
02:40:19 Sugar, Excess Calories, Body Weight
02:49:16 Satiety, Sugar & Calorie Budget
02:54:56 Tool: Individualization, Context & Diet Psychology
02:57:22 Seed Oils, Butter, Olive Oil
03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits
03:13:43 Saturated Fat, Cholesterol; Seed Oils
03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite
03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer
03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity
03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein
03:57:00 Evidence-Based Approach
04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

#HubermanLab #Nutrition #Fitness

Disclaimer: https://www.hubermanlab.com/disclaimer

Episode description

In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity.

We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health.

We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others.

Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness.

Access the full show notes for this episode: https://www.hubermanlab.com/episode/dr-layne-norton-tools-for-nutrition-fitness

Pre-order Andrew's new book, Protocols: https://protocolsbook.com

*Thank you to our sponsors*
AG1: https://drinkag1.com/huberman
Mateina: https://drinkmateina.com/huberman
Eight Sleep: https://www.eightsleep.com/huberman
Maui Nui: https://mauinuivenison.com/huberman
LMNT: https://drinklmnt.com/huberman

*Huberman Lab Social & Website*
Instagram: https://www.instagram.com/hubermanlab
Threads: https://www.threads.net/@hubermanlab
Twitter: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
LinkedIn: https://www.linkedin.com/in/andrew-huberman
Website: https://www.hubermanlab.com
Newsletter: https://www.hubermanlab.com/newsletter

*Dr. Layne Norton*
Website: https://biolayne.com
REPS Research Review: https://biolayne.com/reps
Carbon Diet Coach: https://www.joincarbon.com
Books: https://biolaynestore.com/collections/accessories
X: https://x.com/BioLayne
Facebook: https://www.facebook.com/LayneNorton
Instagram: https://www.instagram.com/biolayne
TikTok: https://www.tiktok.com/@biolayne
YouTube: https://www.youtube.com/@biolayne1

*Timestamps*
00:00:00 Dr. Layne Norton
00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui
00:06:39 Science-Based Evidence, Mechanism vs. Outcome
00:14:31 Meta-analysis, Methods, Evidence Quality
00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data
00:33:53 Sponsor: AG1
00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis
00:42:01 Protein Synthesis, Refractory Response; Resistance Training
00:46:05 Protein Intake, Intermittent Fasting & Training
00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis
01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth
01:05:34 Sponsor: LMNT
01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c
01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet
01:19:50 “The Norton Method”; Tool: Consistency
01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest
01:33:50 Mind & Body Effects, Stress; Belief Effects
01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training
01:50:24 Fatigue & Training to Failure, Speed, Strength Training
01:59:06 Tool: Training After 50, Consistency
02:09:12 Fat Cells, Diabetes, Exercise
02:16:50 Metabolism & Age-Related Changes?, Appetite
02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise”
02:33:42 GLP-1 Agonists, Judgement & Obesity
02:40:19 Sugar, Excess Calories, Body Weight
02:49:16 Satiety, Sugar & Calorie Budget
02:54:56 Tool: Individualization, Context & Diet Psychology
02:57:22 Seed Oils, Butter, Olive Oil
03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits
03:13:43 Saturated Fat, Cholesterol; Seed Oils
03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite
03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer
03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity
03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein
03:57:00 Evidence-Based Approach
04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

#HubermanLab #Nutrition #Fitness

Disclaimer: https://www.hubermanlab.com/disclaimer

Mindsip insights from this episode:

Train shy of failure to enhance strength gains

To maximize strength gains, you are likely better off not training to failure very often, as managing fatigue is critical for force production.

Build muscle after 50 with effective training

People over 50 can build the same amount of muscle as a percentage of their starting muscle mass as younger individuals can.

Maintain metabolism by preserving lean muscle mass

Your metabolism stays relatively flat from age 20 to 70, and any decline is almost entirely explained by the loss of lean muscle mass, not age itself.

Swap butter for seed oils to improve metabolic health

When calories are matched, swapping saturated fats like butter for polyunsaturated fats from seed oils appears to be neutral or beneficial for metabolic health markers.

Choose diet drinks over water to enhance weight loss

When replacing sugary drinks, people on average lose slightly more weight with diet drinks than with water, possibly because the sweet taste helps satisfy cravings.

Explore collagen's role in skin tissue regeneration

While still unproven, a plausible mechanism for collagen improving skin is that its unique amino acids, like glycine, are absorbed and become available for building new tissue.

Understand pathways to clarify health outcomes

Just because a biochemical pathway exists does not mean it will produce a specific health outcome, but if an outcome exists, there is always a mechanism to explain it.

Time meals to maximize muscle protein synthesis

Muscle protein synthesis peaks around 90 minutes after a meal and returns to baseline by three hours, even if amino acid levels in the blood remain high.

Focus on total calories and protein, not carb timing

As long as you control for total daily calories and protein, the specific timing of your carbohydrate intake throughout the day has no significant impact on body composition.

Incorporate resistance training to combat depression

In one study, resistance training just twice a week for 25 minutes had a massive effect size of 1.7 on improving major depressive disorder, far greater than typical SSRIs.

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