Ultra-Processed People: How Big Food Is Rewiring Our Brains | Chris Van Tulleken

Mark Hyman

Apr 16, 2025

Episode description

Ultra-processed food is the new cigarette—and it's fueling a global health crisis hiding in plain sight.

In today’s episode, I’m joined by Dr. Chris van Tulleken—infectious disease physician, BBC broadcaster, and author of Ultra-Processed People—to expose the truth behind ultra-processed foods and the industries driving their consumption. To find out what this food is really doing to us, Dr. van Tulleken became the first subject in a groundbreaking clinical trial—eating 80% of his calories from ultra-processed food for a full month.

We unpack what makes ultra-processed food fundamentally different from real food—even when the ingredients look similar, and why its impact on your brain, metabolism, and long-term health is far worse than anyone thought…

You’ll learn:

  • How ultra-processed food hijacks your brain’s reward system

  • The science behind food addiction and satiety hormones

  • Why food labels and front-of-package claims are designed to mislead you

  • What the latest data says about UPFs and 32 chronic diseases

  • The global policy movements and lawsuits now underway to fight back

This episode is part science, part exposé, and a wake-up call for anyone who thinks food is just about calories and willpower. If you care about your health, your kids, or the future of our food system, you need to hear this.



https://linktr.ee/ultraprocessedpeople



View Show Notes From This Episode

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Episode description

Ultra-processed food is the new cigarette—and it's fueling a global health crisis hiding in plain sight.

In today’s episode, I’m joined by Dr. Chris van Tulleken—infectious disease physician, BBC broadcaster, and author of Ultra-Processed People—to expose the truth behind ultra-processed foods and the industries driving their consumption. To find out what this food is really doing to us, Dr. van Tulleken became the first subject in a groundbreaking clinical trial—eating 80% of his calories from ultra-processed food for a full month.

We unpack what makes ultra-processed food fundamentally different from real food—even when the ingredients look similar, and why its impact on your brain, metabolism, and long-term health is far worse than anyone thought…

You’ll learn:

  • How ultra-processed food hijacks your brain’s reward system

  • The science behind food addiction and satiety hormones

  • Why food labels and front-of-package claims are designed to mislead you

  • What the latest data says about UPFs and 32 chronic diseases

  • The global policy movements and lawsuits now underway to fight back

This episode is part science, part exposé, and a wake-up call for anyone who thinks food is just about calories and willpower. If you care about your health, your kids, or the future of our food system, you need to hear this.



https://linktr.ee/ultraprocessedpeople



View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Sign Up for Dr. Hyman’s Weekly Longevity Journal

https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Mindsip insights from this episode:

Incorporate C15 for cellular strength and metabolism support

C15, found in whole dairy, is a newly discovered essential fatty acid that strengthens cells and supports metabolism, available in a vegan-friendly supplement called Fatty15.

Recognize food additives as indicators of profit-driven design

Industrial ingredients like soy lecithin may not be directly harmful, but they serve as a proxy or sign that a food was designed by a system focused on profit, not health.

Recognize food companies' tactics to engineer addictive products

Major food companies put people in fMRI brain scanners to optimize the 'bliss point' of their products, engineering them to be as addictive as possible.

Implement smart labels to drive food policy action

An effective food policy wouldn't just use warning labels, but would have those labels trigger further regulations like banning cartoon marketing and implementing progressive taxes.

Uncover tobacco industry's tactics in food industry takeover

In the 1980s, tobacco giants like Philip Morris and R.J. Reynolds bought major food companies and applied their addictive product development techniques to food.

Deconstruct junk food to break attachment

To break an attachment to a processed snack like Pringles, try crushing them into a powder and eating it with a spoon to see if you still enjoy the substance without its engineered shape and texture.

Beware of hidden salt and sugar in breakfast cereals

Many ultra-processed foods have a surprisingly uniform formula; your breakfast cereal can be as salty as a microwave lasagna and your pizza as sugary as a dessert.

Avoid ultra-processed foods to restore fullness signals

An ultra-processed diet can blunt your body's fullness hormones and elevate hunger hormones in response to any meal, not just the processed food itself.

Rewire your brain with ultra-processed food awareness

Functional MRI scans showed that eating an ultra-processed diet for four weeks created new brain connections between habit and reward centers, similar to developing an addiction.

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