Why Omega-3 Supplements cause Heart Problems (unless you pay attention to THIS)

Physionic

Aug 21, 2024

Episode description

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References [Use DOI in a Search Engine]
[1] doi:10.3904/kjim.2022.266
[2] doi:10.1161/CIRCULATIONAHA.121.058596
[3] doi:10.1016/j.jacc.2023.05.024
[4] doi:10.1503/cmaj.071356
[5] doi:10.1016/j.biocel.2006.06.014

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#omega3benefits #fishoil #heartdiseaseprevention

Mindsip insights from this episode:

Limit omega-3 intake to reduce heart condition risks

Consuming multiple grams of omega-3s is likely getting into the upper threshold that increases the risk for certain heart conditions.

Balance omega-3 intake to minimize heart disease risk

The health effects of omega-3s likely follow a U-shaped curve, where consuming too little increases one type of heart disease risk, and consuming too much increases another.

Alter gene expression by incorporating omega-3s

In some model systems, exposure to omega-3s can change the gene expression of the very proteins that form ion channels by as much as 50%.

Understand how omega-3s can trigger arrhythmia

By making the cell membrane more fluid, omega-3s can cause ion channels to open more readily, letting in excess sodium and calcium which can prematurely activate heart cells.

Incorporate omega-3s to enhance heart cell membrane fluidity

Once incorporated into the cell membrane of heart cells, omega-3s change the fluidity of the membrane, making it less stiff.

Consume omega-3s to mitigate heart arrhythmia risk

The consumption of omega-3 fats is very likely causative to heart conditions like atrial fibrillation, where a part of your heart has an abnormal rhythm.

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