
Your Brain on Fish Oil - What Happens?
Physionic
May 30, 2025
Mindsip insights from this episode:
Calm brain's immune cells to promote healing
Efoxes bind to the brain's immune cells, called microglia, convincing them to switch from an inflammatory 'attack' phase to a 'clean and repair' phase.
Activate PPAR gamma to combat inflammation
Activated by Omega-3s, the protein PPAR gamma 'bullies' the pro-inflammatory pathway NF kappa B by stealing its activators and physically blocking it from inflammatory genes.
Tag proteins with omega-3s to combat inflammation
Omega-3s cause a tag to be attached to the PPAR gamma protein, allowing it to pick up 'hitchhikers' that help block inflammatory genes inside the cell's nucleus.
Enhance neurotransmitter efficiency with omega-3s
Omega-3s increase synapsin proteins, which create a larger reserve pool of vesicles packed with neurotransmitters, improving the efficiency of brain cell communication.
Transform omega-3s into anti-inflammatory Efoxes for better health
When enzymes in your brain interact with Omega-3s, they convert them into unique anti-inflammatory molecules called Efoxes.
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