Combining Two Supplements to Maximize Eye Health

Physionic

Oct 28, 2024

Episode description

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Created with Biorender

References
[Study 312] Ma L, Liu R, Du JH, Liu T, Wu SS, Liu XH. Lutein, Zeaxanthin and Meso-zeaxanthin Supplementation Associated with Macular Pigment Optical Density. Nutrients. 2016;8(7):426. Published 2016 Jul 12. doi:10.3390/nu8070426

Funding/Conflicts: No Funding / No Conflicts

[Study 311] Mrowicka M, Mrowicki J, Kucharska E, Majsterek I. Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration-Neurodegenerative Disease. Nutrients. 2022;14(4):827. Published 2022 Feb 16. doi:10.3390/nu14040827

[Study 310] Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Adv Nutr. 2021;12(6):2244-2254. doi:10.1093/advances/nmab071

Funding/Conflicts: Non-Profit Funding [International Life Sciences Institute (ILSI) North America Bioactive Committee] // Unknown conflicts

[Study 314] Stringham JM, O'Brien KJ, Stringham NT. Macular carotenoid supplementation improves disability glare performance and dynamics of photostress recovery. Eye Vis (Lond). 2016;3:30. Published 2016 Nov 11. doi:10.1186/s40662-016-0060-8

Funding / Conflicts: Industry Funded [OmniActive Health Technologies] // No declared conflicts of interest

Funding/Conflicts: Public Funding [National Science Center and Grant from Medical University] // No Conflicts of Interest

[Study 313] Nolan JM, Power R, Stringham J, et al. Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: Central Retinal Enrichment Supplementation Trials - Report 1. Invest Ophthalmol Vis Sci. 2016;57(7):3429-3439. doi:10.1167/iovs.16-19520

Funding / Conflicts: Public Funding (European Research Council (ERC)) // No Conflicts of Interest

[A] Goodrow EF, Wilson TA, Houde SC, et al. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations. J Nutr. 2006;136(10):2519-2524. doi:10.1093/jn/136.10.2519

[Study 315] Stringham JM, Stringham NT. Serum and retinal responses to three different doses of macular carotenoids over 12 weeks of supplementation. Exp Eye Res. 2016;151:1-8. doi:10.1016/j.exer.2016.07.005

Funding/Conflicts: Industry Funding [Omniactive Health Technologies] / No Conflicts

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#eyehealth #eyehealthawareness

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H


Created with Biorender

References
[Study 312] Ma L, Liu R, Du JH, Liu T, Wu SS, Liu XH. Lutein, Zeaxanthin and Meso-zeaxanthin Supplementation Associated with Macular Pigment Optical Density. Nutrients. 2016;8(7):426. Published 2016 Jul 12. doi:10.3390/nu8070426

Funding/Conflicts: No Funding / No Conflicts

[Study 311] Mrowicka M, Mrowicki J, Kucharska E, Majsterek I. Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration-Neurodegenerative Disease. Nutrients. 2022;14(4):827. Published 2022 Feb 16. doi:10.3390/nu14040827

[Study 310] Wilson LM, Tharmarajah S, Jia Y, Semba RD, Schaumberg DA, Robinson KA. The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Adv Nutr. 2021;12(6):2244-2254. doi:10.1093/advances/nmab071

Funding/Conflicts: Non-Profit Funding [International Life Sciences Institute (ILSI) North America Bioactive Committee] // Unknown conflicts

[Study 314] Stringham JM, O'Brien KJ, Stringham NT. Macular carotenoid supplementation improves disability glare performance and dynamics of photostress recovery. Eye Vis (Lond). 2016;3:30. Published 2016 Nov 11. doi:10.1186/s40662-016-0060-8

Funding / Conflicts: Industry Funded [OmniActive Health Technologies] // No declared conflicts of interest

Funding/Conflicts: Public Funding [National Science Center and Grant from Medical University] // No Conflicts of Interest

[Study 313] Nolan JM, Power R, Stringham J, et al. Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: Central Retinal Enrichment Supplementation Trials - Report 1. Invest Ophthalmol Vis Sci. 2016;57(7):3429-3439. doi:10.1167/iovs.16-19520

Funding / Conflicts: Public Funding (European Research Council (ERC)) // No Conflicts of Interest

[A] Goodrow EF, Wilson TA, Houde SC, et al. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations. J Nutr. 2006;136(10):2519-2524. doi:10.1093/jn/136.10.2519

[Study 315] Stringham JM, Stringham NT. Serum and retinal responses to three different doses of macular carotenoids over 12 weeks of supplementation. Exp Eye Res. 2016;151:1-8. doi:10.1016/j.exer.2016.07.005

Funding/Conflicts: Industry Funding [Omniactive Health Technologies] / No Conflicts

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#eyehealth #eyehealthawareness

Mindsip insights from this episode:

Supplement vision improvement with realistic expectations

Studies show that supplementing with these molecules has a neutral to positive effect, improving some visual tests but not all of them.

Prioritize zeaxanthin for macula health over lutein

Zeaxanthin has a much greater specificity for the macula, the central part of your eye, while lutein is more evenly spread across the retina.

Utilize dual antioxidant mechanisms to enhance cellular protection

These molecules not only neutralize damaging reactive oxygen species but also integrate into the cell membrane to recruit other antioxidant proteins.

Assess eye health with Macular Pigment Optical Density (MPOD)

A popular clinical measure called Macular Pigment Optical Density (MPOD) is used to assess the natural protective filter in the eye.

Choose lutein and zeaxanthin supplements for superior eye health

A systematic review of 46 studies concluded that supplementation with lutein and zeaxanthin is more potent for improving eye health than whole food sources.

Choose plant-based sources over eggs for lutein intake

While eggs do contain lutein, the amount is at least 40 times less than potent plant-based sources like kale and spinach.

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