
Preventing Aging Mitochondria through Exercise
Physionic
Mar 26, 2025
Mindsip insights from this episode:
Maintain activity to keep muscle physiology youthful
The muscle physiology of active older individuals can be more similar to that of young active individuals than to sedentary people of their own age.
Understand mitochondrial gains across age groups
While exercise improves mitochondrial proteins by a similar relative percentage in young and old, the absolute improvement is smaller in older adults due to a lower starting baseline.
Enhance mitochondrial dynamics through exercise
Exercise increases the proteins responsible for mitochondrial fusion (merging) and fission (splitting) in both young and older individuals.
Maintain cellular energy production through activity
Active individuals, regardless of age, can generate the same amount of cellular energy (ATP) per unit of time from their mitochondria.
Engage in activity to preserve mitochondrial proteins
Active groups, regardless of age, have greater and comparable levels of key mitochondrial proteins relative to sedentary older individuals.
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