Thomas DeLauer: A Fat Loss Peptide more powerful than GLP-1?

Episode description

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0:00 - Introduction
0:53 - MOTS-c on Fat Metabolism inside the Cells
2:53 - Blocking Fat Gain
4:49 - How does MOTS-c work?
5:58 - Some Cautions..
7:00 - Whole Body Fat Metabolism and Age Effect
8:12 - Human Data
10:07 - Main Points

Reference
[Study 439] Reynolds, J.C., Lai, R.W., Woodhead, J.S.T., Joly, J.H., Mitchell, C.J., Cameron-Smith, D., Lu, R., Cohen, P., Graham, N.A., Benayoun, B.A., Merry, T.L., & Lee, C. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun. 2021;12(1):470. doi:10.1038/s41467-020-20790-0.

Funding/Conflicts: Mixed Funding [American Federation for Aging Research (AFAR), National Institute on Aging (T32 AG052374, P01AG034906, R00AG049934, R01AG052258), USC Manning Endowed Fellowship (to J.C.R.), Mork Graduate Fellowship, USC Viterbi School of Engineering (to J.H.J.), USC Viterbi School of Engineering (to N.A.G.), Rose Hills Foundation (innovator grant), NAVIGAGE Foundation (seed grant), Hanson-Thorell Family, Rutherford Discovery Fellowship and Marsden Fund Fast Start Grant (to T.L.M.), Ellison Medical Foundation (EMF)] // Potential direct Conflicts of Interest [Two authors, P.C. and C.L., are listed as consultants and shareholders of CohBar, Inc., a biotechnology company focused on mitochondrial-derived peptides, including MOTS-c; All other authors declared no competing interests]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#mots #peptides #peptidetherapy

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:53 - MOTS-c on Fat Metabolism inside the Cells
2:53 - Blocking Fat Gain
4:49 - How does MOTS-c work?
5:58 - Some Cautions..
7:00 - Whole Body Fat Metabolism and Age Effect
8:12 - Human Data
10:07 - Main Points

Reference
[Study 439] Reynolds, J.C., Lai, R.W., Woodhead, J.S.T., Joly, J.H., Mitchell, C.J., Cameron-Smith, D., Lu, R., Cohen, P., Graham, N.A., Benayoun, B.A., Merry, T.L., & Lee, C. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nat Commun. 2021;12(1):470. doi:10.1038/s41467-020-20790-0.

Funding/Conflicts: Mixed Funding [American Federation for Aging Research (AFAR), National Institute on Aging (T32 AG052374, P01AG034906, R00AG049934, R01AG052258), USC Manning Endowed Fellowship (to J.C.R.), Mork Graduate Fellowship, USC Viterbi School of Engineering (to J.H.J.), USC Viterbi School of Engineering (to N.A.G.), Rose Hills Foundation (innovator grant), NAVIGAGE Foundation (seed grant), Hanson-Thorell Family, Rutherford Discovery Fellowship and Marsden Fund Fast Start Grant (to T.L.M.), Ellison Medical Foundation (EMF)] // Potential direct Conflicts of Interest [Two authors, P.C. and C.L., are listed as consultants and shareholders of CohBar, Inc., a biotechnology company focused on mitochondrial-derived peptides, including MOTS-c; All other authors declared no competing interests]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#mots #peptides #peptidetherapy