Taurine: A Savior against Metabolic Syndrome… or is it?

Physionic

Oct 16, 2024

Episode description

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References
[Study 347] Tzang CC, Chi LY, Lin LH, et al. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. Nutr Diabetes. 2024;14(1):29. Published 2024 May 16. doi:10.1038/s41387-024-00289-z

Public Funding: National Taiwan University Hospital and the Ministry of Science and Technology // No Conflicts of Interest

[1] Sun Q, Wang B, Li Y, et al. Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study. Hypertension. 2016;67(3):541-549. doi:10.1161/HYPERTENSIONAHA.115.06624

[2] DiNicolantonio JJ, OKeefe JH, McCarty MF. Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health. Open Heart. 2017;4(1):e000600. Published 2017 May 22. doi:10.1136/openhrt-2017-000600

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#taurine #metabolicsyndrome

Episode description

Mindsip insights from this episode:

Determine effective taurine dosage between 0.5 to 6 grams daily

The studies analyzed used a wide range of taurine doses, from 0.5 grams to 6 grams per day, to achieve their effects.

#dosage

#supplement

Utilize taurine to relax blood vessels and improve circulation

By increasing hydrogen sulfide, taurine helps potassium leak out of smooth muscle cells, making them more negative and less likely to contract, thus keeping blood vessels relaxed.

#blood-flow

#supplement

Boost hydrogen sulfide production with taurine

Taurine doesn't convert into hydrogen sulfide itself, but rather increases the production of enzymes that create this beneficial molecule from other amino acids.

#hydrogen

#supplement

Utilize taurine to support blood pressure reduction through hydrogen sulfide production

Taurine may lower blood pressure not directly, but by increasing your cells' production of hydrogen sulfide, a molecule that helps relax blood vessels.

#blood-pressure

#hydrogen

Supplement taurine to lower blood pressure, blood sugar, and triglycerides

In a meta-analysis, taurine supplementation showed a mild protective effect, reducing blood pressure by about 4 points, blood sugar by almost 6 points, and triglycerides by 18 points.

#blood-pressure

#supplement

Critique methodological flaws in taurine meta-analysis

The reviewed meta-analysis is weakened by methodological issues, such as mixing different types of control groups and failing to analyze if specific subgroups benefited more than others.