Why Scientists disagree with Longevity Biohacker Bryan Johnson, New Study

Physionic

Oct 30, 2024

Episode description

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Reference
[Study 349] Olshansky SJ, Willcox BJ, Demetrius L, Beltrán-Sánchez H. Implausibility of radical life extension in humans in the twenty-first century. Nat Aging. Published online October 7, 2024. doi:10.1038/s43587-024-00702-3

Public Funding: National Institute of Aging and National Institute of Child Health and Human Development // No Conflicts of Interest

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Episode description

Mindsip insights from this episode:

Address slowing progress in lifespan improvement

A new study shows that across most countries with the highest life expectancy, the rate of improvement has fallen below the historical 0.3% annual threshold, indicating a deceleration in our progress.

#aging

#lifespan

Explore potential of gero-therapeutic research beyond disease model

The study's pessimistic outlook is based on a 'disease model of life,' and the speakers note the frontier is wide open when considering the potential of gero-therapeutic (anti-aging) research.

#aging

#anti-aging

Defy averages to become an outlier in longevity

This research is about population averages and doesn't mean an individual can't become an extreme outlier, like living to 105 when the average is 80.

#longevity

Improve foundational health to enable advanced science for longevity

Advanced science can't do much for longevity on a 'broken foundation,' so improving foundational health like nutrition and exercise is the critical first step.

#longevity

#nutrition

Address challenges of extreme aging to improve life expectancy

To increase the average life expectancy from 109 to 110 years old, death rates would have to be 88% lower, highlighting the immense difficulty of surviving at extreme ages.

#aging

#lifespan

Aim for 6% of women to reach 150 for radical life expectancy gains

To achieve radical life expectancy improvements similar to those seen in the past, researchers calculate that 6% of women would need to survive to be 150 years old.