
The Multiple Mechanisms Fish Oil affects your Heart
Physionic
Nov 13, 2024
Mindsip insights from this episode:
Block fat-producing genes with omega-3s
Omega-3s can enter the cell's nucleus and competitively bind to DNA, thereby blocking proteins that would normally activate genes for triglyceride synthesis.
Activate GPR120 with omega-3s to reduce inflammation
Omega-3s bind to and activate a specific cellular receptor called GPR120, which inhibits the production of inflammatory molecules that can cause insulin resistance.
Reduce cellular fats to combat insulin resistance
An accumulation of specific fat molecules called DAGs and ceramides inside your cells can directly inhibit the insulin signaling pathway, causing insulin resistance.
Destroy fat-production instructions with omega-3s
Omega-3s can destabilize the messenger RNA (mRNA) from fat-producing genes, causing it to be destroyed before it can be used to create triglyceride-forming enzymes.
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